Synthesis of Functionalized Nanoparticles for Biomedical Applications

  • Priti Kumari
  • Niraj Kumari
  • Anal K. Jha
  • K. P. Singh
  • Kamal PrasadEmail author
Part of the Nanotechnology in the Life Sciences book series (NALIS)


Nanoscience and Technology has emerged as a potentially promising field which encompasses physics, chemistry, biology, engineering science, medical science, material sciences, etc. This prodigal branch ensures production and manipulation of materials at the nanometer scale, thereby witnessing amazing applications in every field including biomedical sciences. The time and capital intensity along with potential annihilation to the environment led to the emergence of green protocols for the synthetic cues. It unfolded slowly and gained quantum popularity within a very short span of time. One can ensure synthesis of different metal/oxide with aptness and amenability for different applications. Health has been our prime concern since our inception on this planet and that might have compelled the human beings to peruse nature for remedies. Plants have always been our first choice for food, medicine, cloth, and shelter. It must have been quite exciting for our ancient harbingers to reckon plants as source of medicine and a therapeutic mean to alleviate ailments. Ayurveda—our ancient treasure of knowledge—is a wonderful source that delineates the interaction between metal salts and herb extracts, better known as Shodhan in ayurvedic cues, today better known as functional nanomaterials. Later on, we realized with time that plants have treasures of primary and secondary metabolites like flavonoids, alkaloids, steroids, poly phenols, saponins, tannins, and other compounds, which act as reducing and stabilizing agents for the bioreduction reaction to synthesized novel metal nanoparticles. So, our glorious ancient mythology has emerged as a prodigally promising technology. The green synthesized nanoparticles have effectively been used to control the various endemic diseases such as malaria, cancer, HIV, hepatitis, and other acute diseases. Recently, nanoparticles of silver and gold are found extremely useful for different applications such as in optoelectronic devices, ultrasensitive chemical sensor, biosensors, catalysts, separation sciences, drug delivery, DNA and RNA analysis, gene therapy, antimicrobial agent, etc. This chapter discusses the biosynthesis of metal nanoparticles using medicinal plant and/or plant parts, which enhance the medicinal values. Also, discussed the role of primary as well as secondary metabolites of different plant and/or plant parts in accomplishing the nanotransformation, bioreduction, and stabilization of nanoparticles.


Fabrication Functionalized nanoparticles Silver nanoparticles Antimicrobial Anticancer Phytochemicals 


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Copyright information

© Springer Nature Switzerland AG 2018

Authors and Affiliations

  • Priti Kumari
    • 1
  • Niraj Kumari
    • 1
  • Anal K. Jha
    • 1
  • K. P. Singh
    • 2
  • Kamal Prasad
    • 3
    Email author
  1. 1.Aryabhatta Centre for Nanoscience and NanotechnologyAryabhatta Knowledge UniversityPatnaIndia
  2. 2.University Department of ZoologyVinoba Bhave UniversityHazaribagIndia
  3. 3.Department of PhysicsTilka Manjhi Bhagalpur UniversityBhagalpurIndia

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