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Plant-Derived Drugs Affecting GPRCs

  • Angelika BöttgerEmail author
  • Ute Vothknecht
  • Cordelia Bolle
  • Alexander Wolf
Chapter
Part of the Learning Materials in Biosciences book series (LMB)

Abstract

The presence of GPRCs in plants is still a question of debate. While G-protein coupled signalling exists, the signalling cycle is typically not activated by seven transmembrane-spanning receptors. By contrast, many plant secondary metabolites are known to affect human GPRCs. Some are very specific for a single type of receptor; however, many others act on more than one type, albeit with often strongly different affinities.

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© Springer Nature Switzerland AG 2018

Authors and Affiliations

  • Angelika Böttger
    • 1
    Email author
  • Ute Vothknecht
    • 2
  • Cordelia Bolle
    • 3
  • Alexander Wolf
    • 4
  1. 1.Department Biology IILMU MunichPlanegg-MartinsriedGermany
  2. 2.IZMB-Plant Cell BiologyUniversity of BonnBonnGermany
  3. 3.Department Biology ILMU MunichPlanegg-MartinsriedGermany
  4. 4.Inst. Molecular Toxicology/PharmacologyHelmholtz Zentrum MünichNeuherbergGermany

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