Pain pp 311-314 | Cite as

Ziconotide Intrathecal Therapy

  • Samita S. Das
  • Salim M. HayekEmail author


Ziconotide is a non-opioid, potent intrathecal analgesic with mechanism of action involving interruption of spinal neurotransmission approved by the Food and Drug Administration in 2004 for the treatment of severe refractory chronic pain. Presented are pertinent diagnoses and proper patient selection for ziconotide therapy, guidelines for treatment, and current evidence for analgesic efficacy and safety for intrathecal use.


Ziconotide Intrathecal analgesia N-type calcium channel blocker 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of Anesthesiology: Division of Pain MedicineUniversity Hospitals Cleveland Medical CenterClevelandUSA

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