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Pain pp 1279-1281 | Cite as

Sickle Cell Disease

  • Matt Fischer
  • Harsh Sachdeva
  • Alaa Abd-ElsayedEmail author
Chapter

Abstract

Sickle cell disease is a genetic disorder of red blood cells that predisposes patients to acute and chronic pain. Acute pain crises, or vaso-occlusive crises, should be treated expeditiously to avoid other complications of sickle cell disease. Management of crises includes supportive care as well as multimodal analgesia.

Keywords

Sickle cell disease Pain crisis Vaso-occlusive crisis Multimodal analgesia 

References

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    McClish DK, Smith WR, Dahman BA, et al. Pain site frequency and location in sickle cell disease: the PiSCES project. Pain. 2009;145(1–2):246–51.CrossRefGoogle Scholar
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    Niscola P, Sorrentino F, Scaramucci L, et al. Pain syndromes in sickle cell disease: an update. Pain Med. 2009;10(3):470–80.CrossRefGoogle Scholar
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    Beers EJ, van Tuijn CF, Nieuwkerk PT, et al. Patient-controlled analgesia versus continuous infusion of morphine during vaso-occlusive crisis in sickle cell disease, a randomized controlled trial. Am J Hematol. 2007;82(11):955–60.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Matt Fischer
    • 1
  • Harsh Sachdeva
    • 2
  • Alaa Abd-Elsayed
    • 1
    Email author
  1. 1.Department of AnesthesiologyUniversity of Wisconsin School of Medicine and Public HealthMadisonUSA
  2. 2.University of Cincinnati College of MedicineCincinnatiUSA

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