Pain pp 1139-1141 | Cite as

Pharmacologic Treatment of Patients with Addiction

  • Farnad ImaniEmail author


Effective pharmacotherapy is a valuable tool to treat addiction disorders. It has included partial μ agonist, such as buprenorphine, and μ opioid agonists, such as methadone. The pharmacological basis of maintenance treatment of dependent individuals is to minimize withdrawal symptoms.


Addiction Buprenorphine Methadone 


  1. 1.
    Fudala PJ, Bridge TP, Herbert S, et al. Office-based treatment of opiate addiction with a sublingual tablet formulation of buprenorphine and naloxone. N Engl J Med. 2003;349:949–58.CrossRefGoogle Scholar
  2. 2.
    Maxwell JC, McCance-Katz EF. Indicators of buprenorphine and methadone use and abuse: what do we know? Am J Addict. 2010;19:73–88.CrossRefGoogle Scholar
  3. 3.
    Faggiano F, Vigna-Taglianti F, Versino E, Lemma P. Methadone maintenance at different dosages for opioid dependence. Co-chrane Database Syst Rev. 2003;3:CD002208.Google Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Pain Research Center, Department of Anesthesiology and Pain MedicineIran University of Medical SciencesTehranIran

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