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Pain pp 911-913 | Cite as

Diabetic Peripheral Neuropathy

  • Blake Watterworth
  • Thelma B. WrightEmail author
Chapter

Abstract

Diabetic peripheral neuropathy describes a variety of neuropathic conditions caused by diabetes mellitus. It is a common complication of the disease. The pathophysiology is incompletely understood but involves multifactorial mechanisms of nerve injury that lead to a painful disease state. Multiple pharmacologic treatments exist which may reduce the symptoms of disease. These include anticonvulsants, antidepressants, opioids, and topical medications. Little can be done to reverse the progression of disease, and ultimately good glycemic control is the cornerstone of prevention.

Keywords

Diabetic peripheral neuropathy Neuropathic pain Diabetes 

References

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    Bril V, England JD, Franklin GM, et al. Evidence-based guideline: treatment of painful diabetic neuropathy-report of the american association of neuromuscular and electrodiagnostic medicine, the american academy of neurology, and the american academy of physical medicine & amp; rehabilitation. Muscle Nerve. 2011;43:910–7.CrossRefGoogle Scholar
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    Wiffen PJ, Derry S, Bell RF, et al. Gabapentin for chronic neuropathic pain in adults. Cochrane Database Syst Rev. 2017;6:CD007938.PubMedGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of AnesthesiologyUniversity of Maryland School of MedicineBaltimoreUSA
  2. 2.Pain Management CenterGwynn OakUSA

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