Pain pp 895-898 | Cite as

Kyphoplasty and Vertebroplasty

  • Vikas K. Parmar
  • Daniel K. ResnickEmail author


Vertebral body compression fractures are ubiquitous and a source of severe pain for many patients. Conservative treatment including bracing and physical therapy is effective for most patients. However patients with a non-healing vertebral body fracture and significant pain lasting >6 weeks but <1 year and with point tenderness corresponding to the location of vertebral body fracture can potentially have some benefit from vertebroplasty (cement augmentation into the fracture space) or kyphoplasty (balloon dilation typically followed by cement augmentation). Prospective randomized studies have demonstrated some improvement in pain; whereas, sham studies have demonstrated no benefit. Overall, with good patient selection vertebroplasty and kyphoplasty can be a beneficial tool to help patients with pain due to compression fractures, spinal metastasis, or multiple myeloma.


Vertebral compression fracture Vertebroplasty Kyphoplasty 


  1. 1.
    Gangi A, Kastler BA, Dietemann JL. Percutaneous vertebroplasty guided by a combination of CT and fluoroscopy. AJNR Am J Neuroradiol. 1994;15:83–6.PubMedGoogle Scholar
  2. 2.
    Taylor RA, Fritzell P, Taylor RJ. Balloon kyphoplasty in the management of vertebral compression fractures: an updated systematic review and meta-analysis. Eur Spine J. 2007;16:1085–100.CrossRefGoogle Scholar
  3. 3.
    Kallmes DF, Comstock BA, Heagerty PJ, Turner JA, Wilson DJ, Diamond TH, et al. A randomized trial of vertebroplasty for osteoporotic spinal fractures. N Engl J Med. 2009;361:569–79.CrossRefGoogle Scholar
  4. 4.
    Buchbinder R, Osborne RH, Ebeling PR, Wark JD, Mitchell P, Wriedt C, et al. A randomized trial of vertebroplasty for painful osteoporotic vertebral fractures. N Engl J Med. 2009;361:557–68.CrossRefGoogle Scholar
  5. 5.
    Berenson J, Pflugmacher R, Jarzem P, Zonder J, Schechtman K, et al. Balloon kyphoplasty versus non-surgical fracture management for treatment of painful vertebral body compression fractures in patients with cancer: a multicentre, randomised controlled trial. Lancet Oncol. 2011;12(3):225–35.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of NeurosurgeryUniversity of Wisconsin School of Medicine and Public HealthMadisonUSA

Personalised recommendations