Pain pp 865-868 | Cite as

Surgical Lesioning of the Brain, Brain Stem, Spinal Cord, and Nerves

  • Mark Corriveau
  • Amgad S. HannaEmail author


Intractable pain from malignancy or other causes can be debilitating. When medical management fails, surgical treatment can be considered. Different techniques of surgical lesioning are presented here.


Dorsal root entry zone (DREZ) Ganglionectomy Mesencephalotomy Nucleus caudalis Rhizotomy 


  1. 1.
    Kim DR, Lee SW, Son BC. Stereotactic mesencephalotomy for cancer – related facial pain. J Korean Neurosurg Soc. 2014;56(1):71–4.CrossRefGoogle Scholar
  2. 2.
    Kanpolat Y, Tuna H, Bozkurt M, Elhan AH. Spinal and nucleus caudalis dorsal root entry zone operations for chronic pain. Neurosurgery. 2008;62(3 Suppl 1):235–42. discussion 242–234.PubMedGoogle Scholar
  3. 3.
    Jeanmonod D, Sindou M. Somatosensory function following dorsal root entry zone lesions in patients with neurogenic pain or spasticity. J Neurosurg. 1991;74(6):916–32.CrossRefGoogle Scholar
  4. 4.
    Burchiel KJ, Ochoa JL. Surgical management of post-traumatic neuropathic pain. Neurosurg Clin N Am. 1991;2(1):117–26.CrossRefGoogle Scholar
  5. 5.
    Cetas JS, Saedi T, Burchiel KJ. Destructive procedures for the treatment of nonmalignant pain: a structured literature review. J Neurosurg. 2008;109(3):389–404.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of NeurosurgeryUniversity of WisconsinMadisonUSA

Personalised recommendations