Biomolecules Assisted Synthesis of Metal Nanoparticles

  • Meryam SardarEmail author
  • Jahirul Ahmed Mazumder
Part of the Environmental Chemistry for a Sustainable World book series (ECSW, volume 21)


The synthesis of metal nanoparticles is an upcoming area of research as these nanoparticles have applications in diverse field. These are beneficial to human beings as they can be used for targeting the diseases like cancer, used as therapeutic agents, as biosensors and in imaging. These are also employed in removal of heavy metals and phenolic pollutants from soil and water and have excellent catalytic properties. Thus, there is a need to develop the protocols or methods which can synthesize these nanoparticles at large scale, also the methods should be environment friendly and economical. Lot of reviews have been published so far on the techniques and methods of synthesis of these nanoparticles citing the advantage and disadvantage of each method. In this chapter biosynthesis of metal nanoparticles have been described, the synthesis of silver and gold nanoparticles is discussed at length. These can be synthesized by physical, chemical and biological methods. Biological methods are considered better over other methods of synthesis as they do not employ any toxic chemicals or reagents; only the biomolecules present in the organisms serves as the reducing and stabilizing agent. In nature we have a great diversity of plants and animals available to us, thus have a wider choice of the reducing agents which can reduce the metal ions. Multicellular and unicellular organisms are known to accumulate metals; this property is mainly exploited in the synthesis process.


Biosynthesis Metal nanoparticles Green synthesis Enzymatic synthesis Silver nanoparticles Gold nanoparticles 



The financial support provided by the Indian Council of Medical Research (ICMR), Government of India, is greatly acknowledged.


  1. Ahmad A, Mukherjee P, Senapati S, Mandal D, Khan MI, Kumar R, Sastry M (2003) Extracellular biosynthesis of silver nanoparticles using the fungus fusarium oxysporum. Colloids Surf B: Biointerfaces 28:313–318CrossRefGoogle Scholar
  2. Ahmad T, Wani IA, Manzoor N, Ahmed J, Asiri AM (2013) Biosynthesis, structural characterization and antimicrobial activity of gold and silver nanoparticles. Colloids Surf B: Biointerfaces 107:227–234CrossRefGoogle Scholar
  3. Ahmadi TS, Wang ZL, Green TC, Henglein A, El-Sayed MA (1996) Shape-controlled synthesis of colloidal platinum nanoparticles. Science 272:1924–1925CrossRefGoogle Scholar
  4. Albanese A, Tang PS, Chan WC (2012) The effect of nanoparticle size, shape, and surface chemistry on biological systems. Annu Rev Biomed Eng 14:1–16CrossRefGoogle Scholar
  5. Alivisatos P (2004) The use of nanocrystals in biological detection. Nat Biotechnol 22:47–52CrossRefGoogle Scholar
  6. Amendola V, Riello P, Meneghetti M (2010) Magnetic nanoparticles of iron carbide, iron oxide, iron@ iron oxide, and metal iron synthesized by laser ablation in organic solvents. J Phys Chem C 115:5140–5146CrossRefGoogle Scholar
  7. Amin M, Anwar F, Janjua MRSA, Iqbal MA, Rashid U (2012) Green synthesis of silver nanoparticles through reduction with Solanum xanthocarpum L. berry extract: characterization, antimicrobial and urease inhibitory activities against Helicobacter pylori. Int J Mol Sci 13:9923–9941CrossRefGoogle Scholar
  8. Amin M, Alazba A, Manzoor U (2014) A review of removal of pollutants from water/wastewater using different types of nanomaterials. Adv Mater Sci Eng 2014:1CrossRefGoogle Scholar
  9. Annamalai J, Nallamuthu T (2016) Green synthesis of silver nanoparticles: characterization and determination of antibacterial potency. Appl Nanosci 6:259–265CrossRefGoogle Scholar
  10. Ayala Valencia G, Cristina de Oliveira Vercik L, Ferrari R, Vercik A (2013) Synthesis and characterization of silver nanoparticles using water-soluble starch and its antibacterial activity on Staphylococcus aureus. Starch-Stärke 65:931–937CrossRefGoogle Scholar
  11. Azizi S, Namvar F, Mahdavi M, Ahmad MB, Mohamad R (2013) Biosynthesis of silver nanoparticles using brown marine macroalga, Sargassum muticum aqueous extract. Materials 6:5942–5950CrossRefGoogle Scholar
  12. Azizi S, Ahmad MB, Namvar F, Mohamad R (2014) Green biosynthesis and characterization of zinc oxide nanoparticles using brown marine macroalga Sargassum muticum aqueous extract. Mater Lett 116:275–277CrossRefGoogle Scholar
  13. Badawy AME, Luxton TP, Silva RG, Scheckel KG, Suidan MT, Tolaymat TM (2010) Impact of environmental conditions (pH, ionic strength, and electrolyte type) on the surface charge and aggregation of silver nanoparticles suspensions. Environ Sci Technol 44:1260–1266CrossRefGoogle Scholar
  14. Balaji D, Basavaraja S, Deshpande R, Mahesh DB, Prabhakar B, Venkataraman A (2009) Extracellular biosynthesis of functionalized silver nanoparticles by strains of Cladosporium cladosporioides fungus. Colloids Surf B: Biointerfaces 68:88–92CrossRefGoogle Scholar
  15. Balaji S, Mandal BK, Ranjan S, Dasgupta N, Ramalingam C (2017) Nano-zirconia – evaluation of its antioxidant and anticancer activity. J Photochem Photobiol B Biol 170:125–133. CrossRefGoogle Scholar
  16. Balasundaram G, Sato M, Webster TJ (2006) Using hydroxyapatite nanoparticles and decreased crystallinity to promote osteoblast adhesion similar to functionalizing with RGD. Biomaterials 27:2798–2805CrossRefGoogle Scholar
  17. Banerjee A, Bandopadhyay R (2016) Use of dextran nanoparticle: a paradigm shift in bacterial exopolysaccharide based biomedical applications. Int J Biol Macromol 87:295–301CrossRefGoogle Scholar
  18. Baruah D, Konwar D (2015) Cellulose supported copper nanoparticles as a versatile and efficient catalyst for the protodecarboxylation and oxidative decarboxylation of aromatic acids under microwave heating. Catal Commun 69:68–71CrossRefGoogle Scholar
  19. Bhattacharya D, Gupta RK (2005) Nanotechnology and potential of microorganisms. Crit Rev Biotechnol 25:199–204CrossRefGoogle Scholar
  20. Bhuvaneswari R, Xavier RJ, Arumugam M (2016) Larvicidal property of green synthesized silver nanoparticles against vector mosquitoes (Anopheles stephensi and Aedes aegypti). J King Saud Univ-Sci 28:318–323CrossRefGoogle Scholar
  21. Borase HP, Salunke BK, Salunkhe RB, Patil CD, Hallsworth JE, Kim BS, Patil SV (2014) Plant extract: a promising biomatrix for ecofriendly, controlled synthesis of silver nanoparticles. Appl Biochem Biotechnol 173:1–29CrossRefGoogle Scholar
  22. Brar SK, Verma M, Tyagi R, Surampalli R (2010) Engineered nanoparticles in wastewater and wastewater sludge–evidence and impacts. Waste Manag 30:504–520CrossRefGoogle Scholar
  23. Brust M, Walker M, Bethell D, Schiffrin DJ, Whyman R (1994) Synthesis of thiol-derivatised gold nanoparticles in a two-phase liquid–liquid system. J Chem Soc Chem Commun 0:801–802CrossRefGoogle Scholar
  24. Chandran SP, Chaudhary M, Pasricha R, Ahmad A, Sastry M (2006) Synthesis of gold nanotriangles and silver nanoparticles using Aloevera plant extract. Biotechnol Prog 22:577–583CrossRefGoogle Scholar
  25. Chauhan A et al (2011) Fungus-mediated biological synthesis of gold nanoparticles: potential in detection of liver cancer. Int J Nanomedicine 6:2305–2319Google Scholar
  26. Clark JH, Macquarrie DJ (2008) Handbook of green chemistry and technology. Wiley, New YorkGoogle Scholar
  27. Das M, Saxena N, Dwivedi PD (2009) Emerging trends of nanoparticles application in food technology: safety paradigms. Nanotoxicology 3:10–18CrossRefGoogle Scholar
  28. Das SK, Dickinson C, Lafir F, Brougham DF, Marsili E (2012) Synthesis, characterization and catalytic activity of gold nanoparticles biosynthesized with Rhizopus oryzae protein extract. Green Chem 14:1322–1334CrossRefGoogle Scholar
  29. Dasgupta N, Ranjan S, Mishra D, Ramalingam C (2018) Thermal co-reduction engineered silver nanoparticles induce oxidative cell damage in human colon cancer cells through inhibition of reduced glutathione and induction of mitochondria-involved apoptosis. Chem Biol InteractGoogle Scholar
  30. Dasgupta N, Ranjan S, Mundekkad D, Ramalingam C, Shanker R, Kumar A (2015) Nanotechnology in agro-food: from field to plate. Food Res Int 69:381–400CrossRefGoogle Scholar
  31. Dasgupta N, Ranjan S, Rajendran B, Manickam V, Ramalingam C, Avadhani GS, Kumar A (2016) Thermal co-reduction approach to vary size of silver nanoparticle: its microbial and cellular toxicology. Environ Sci Pollut Res 23(5):4149–4163CrossRefGoogle Scholar
  32. Datta KKR, Reddy BVS, Zboril R (2016) Polysaccharides as functional scaffolds for noble metal nanoparticles and their catalytic applications. In: Encyclopedia of nanoscience and nanotechnology. American Scientific Publishers, Valencia, pp 1–20Google Scholar
  33. Deepak V, Kalishwaralal K, Pandian SRK, Gurunathan S (2011) An insight into the bacterial biogenesis of silver nanoparticles, industrial production and scale-up. In: Metal nanoparticles in microbiology. Springer, Berlin/Heidelberg, pp 17–35CrossRefGoogle Scholar
  34. Djalali R, Chen Y-f, Matsui H (2002) Au nanowire fabrication from sequenced histidine-rich peptide. J Am Chem Soc 124:13660–13661CrossRefGoogle Scholar
  35. Dondi R, Su W, Griffith GA, Clark G, Burley GA (2012) Highly size-and shape-controlled synthesis of silver nanoparticles via a templated Tollens reaction. Small 8:770–776CrossRefGoogle Scholar
  36. Dong C, Zhang X, Cai H (2014) Green synthesis of monodisperse silver nanoparticles using hydroxy propyl methyl cellulose. J Alloys Compd 583:267–271CrossRefGoogle Scholar
  37. dos Santos MA, Grenha A (2015) Chapter seven-polysaccharide nanoparticles for protein and peptide delivery: exploring less-known materials. Adv Protein Chem Struct Biol 98:223–261CrossRefGoogle Scholar
  38. Durán N, Marcato PD, Durán M, Yadav A, Gade A, Rai M (2011) Mechanistic aspects in the biogenic synthesis of extracellular metal nanoparticles by peptides, bacteria, fungi, and plants. Appl Microbiol Biotechnol 90:1609–1624CrossRefGoogle Scholar
  39. El-Batal AI, ElKenawy NM, Yassin AS, Amin MA (2015) Laccase production by Pleurotus ostreatus and its application in synthesis of gold nanoparticles. Biotechnol Rep 5:31–39CrossRefGoogle Scholar
  40. El-Rafie H, El-Rafie M, Zahran M (2013) Green synthesis of silver nanoparticles using polysaccharides extracted from marine macro algae. Carbohydr Polym 96:403–410CrossRefGoogle Scholar
  41. Eugenio M et al (2016) Yeast-derived biosynthesis of silver/silver chloride nanoparticles and their antiproliferative activity against bacteria. RSC Adv 6:9893–9904CrossRefGoogle Scholar
  42. Feynman RP (1960) There’s plenty of room at the bottom. Eng Sci 23:22–36Google Scholar
  43. Fierascu R, IONa R, Dumitriu I (2010) Noble metals nanoparticles synthesis in plant extracts. Synthesis 1:22Google Scholar
  44. Gan Q, Wang T, Cochrane C, McCarron P (2005) Modulation of surface charge, particle size and morphological properties of chitosan–TPP nanoparticles intended for gene delivery. Colloids Surf B: Biointerfaces 44:65–73CrossRefGoogle Scholar
  45. Gao T, Li Q, Wang T (2005) Sonochemical synthesis, optical properties, and electrical properties of core/shell-type ZnO nanorod/CdS nanoparticle composites. Chem Mater 17:887–892CrossRefGoogle Scholar
  46. Gao Z, Su R, Huang R, Qi W, He Z (2014) Glucomannan-mediated facile synthesis of gold nanoparticles for catalytic reduction of 4-nitrophenol. Nanoscale Res Lett 9:404CrossRefGoogle Scholar
  47. Gardea-Torresdey J, Parsons J, Gomez E, Peralta-Videa J, Troiani H, Santiago P, Yacaman MJ (2002) Formation and growth of Au nanoparticles inside live alfalfa plants. Nano Lett 2:397–401CrossRefGoogle Scholar
  48. Garitaonandia JS et al (2008) Chemically induced permanent magnetism in Au, Ag, and Cu nanoparticles: localization of the magnetism by element selective techniques. Nano Lett 8:661–667CrossRefGoogle Scholar
  49. Gholami-Shabani M et al (2015) Enzymatic synthesis of gold nanoparticles using sulfite reductase purified from Escherichia coli: a green eco-friendly approach. Process Biochem 50:1076–1085CrossRefGoogle Scholar
  50. Ghosh S et al (2012) Gnidia glauca flower extract mediated synthesis of gold nanoparticles and evaluation of its chemocatalytic potential. J Nanobiotechnol 10:17CrossRefGoogle Scholar
  51. Golubeva OY, Shamova O, Yakovlev A, Zharkova M (2016) Synthesis and study of the biologically active lysozyme–silver nanoparticles–montmorillonite K10 complexes. Glas Phys Chem 42:87–94CrossRefGoogle Scholar
  52. González-Ballesteros N, Prado-López S, Rodríguez-González J, Lastra M, Rodríguez-Argüelles M (2017) Green synthesis of gold nanoparticles using brown algae Cystoseira baccata: its activity in colon cancer cells. Colloids Surf B: Biointerfaces 153:190–198CrossRefGoogle Scholar
  53. Gottschalk F, Sonderer T, Scholz RW, Nowack B (2009) Modeled environmental concentrations of engineered nanomaterials (TiO2, ZnO, Ag, CNT, fullerenes) for different regions. Environ Sci Technol 43:9216–9222CrossRefGoogle Scholar
  54. Gupta K, Singh R, Pandey A, Pandey A (2013) Photocatalytic antibacterial performance of TiO2 and Ag-doped TiO2 against S. aureus. P. aeruginosa and E. coli. Beilstein J Nanotechnol 4:345–351CrossRefGoogle Scholar
  55. Gurunathan S et al (2009a) Biosynthesis, purification and characterization of silver nanoparticles using Escherichia coli. Colloids Surf B: Biointerfaces 74:328–335CrossRefGoogle Scholar
  56. Gurunathan S, Lee K-J, Kalishwaralal K, Sheikpranbabu S, Vaidyanathan R, Eom SH (2009b) Antiangiogenic properties of silver nanoparticles. Biomaterials 30:6341–6350CrossRefGoogle Scholar
  57. He S, Guo Z, Zhang Y, Zhang S, Wang J, Gu N (2007) Biosynthesis of gold nanoparticles using the bacteria Rhodopseudomonas capsulata. Mater Lett 61:3984–3987CrossRefGoogle Scholar
  58. Honary S, Barabadi H, Gharaei-Fathabad E, Naghibi F (2012) Green synthesis of copper oxide nanoparticles using Penicillium aurantiogriseum, Penicillium citrinum and Penicillium waksmanii. Dig J Nanomater Biostruct 7:999–1005Google Scholar
  59. Honary S, Barabadi H, Gharaei-Fathabad E, Naghibi F (2013) Green synthesis of silver nanoparticles induced by the fungus Penicillium citrinum. Trop J Pharm Res 12:7–11Google Scholar
  60. Hosseini SA, Talebipour S, Neyestani MR, Ranjan S, Dasgupta N (2018) Graphene oxide MgFe2O4 nanocomposites for Cr(VI) remediation: a comparative modeling study. Nanotechnol Environ Eng 3(1)Google Scholar
  61. Hostetler MJ et al (1998) Alkanethiolate gold cluster molecules with core diameters from 1.5 to 5.2 nm: core and monolayer properties as a function of core size. Langmuir 14:17–30CrossRefGoogle Scholar
  62. Huang J et al (2011) Biogenic silver nanoparticles by Cacumen platycladi extract: synthesis, formation mechanism, and antibacterial activity. Ind Eng Chem Res 50:9095–9106CrossRefGoogle Scholar
  63. Hulkoti NI, Taranath T (2014) Biosynthesis of nanoparticles using microbes—a review. Colloids Surf B: Biointerfaces 121:474–483CrossRefGoogle Scholar
  64. Ibrahem KH, Salman JAS, Ali FA (2014) Effect of titanium nanoparticles biosynthesis by Lactobacillus Crispatus on urease, hemolysin & biofilm forming by some bacteria causing recurrent UTI in Iraqi women. Eur Sci J 10Google Scholar
  65. Ingale AG, Chaudhari A (2013) Biogenic synthesis of nanoparticles and potential applications: an eco-friendly approach. J Nanomed Nanotechol 4:1–7CrossRefGoogle Scholar
  66. Iravani S, Korbekandi H, Mirmohammadi S, Zolfaghari B (2014) Synthesis of silver nanoparticles: chemical, physical and biological methods. Res Pharm Sci 9:385Google Scholar
  67. Jain A, Ranjan S, Dasgupta N, Ramalingam C (2017) Nanomaterials in food and agriculture: an overview on their safety concerns and regulatory issues. Crit Rev Food Sci Nutr 58(2):297–317CrossRefGoogle Scholar
  68. Jain PK, Huang X, El-Sayed IH, El-Sayed MA (2008) Noble metals on the nanoscale: optical and photothermal properties and some applications in imaging, sensing, biology, and medicine. Acc Chem Res 41:1578–1586CrossRefGoogle Scholar
  69. Jang J-S, Kim S-J, Choi S-J, Kim N-H, Hakim M, Rothschild A, Kim I-D (2015) Thin-walled SnO 2 nanotubes functionalized with Pt and Au catalysts via the protein templating route and their selective detection of acetone and hydrogen sulfide molecules. Nanoscale 7:16417–16426CrossRefGoogle Scholar
  70. Jha AK, Prasad K, Prasad K (2009) A green low-cost biosynthesis of Sb 2 O 3 nanoparticles. Biochem Eng J 43:303–306CrossRefGoogle Scholar
  71. Jia J-L, Xu H-H, Zhu L, Ye W-H, Li D-Q (2015) Biosynthesis of gold nanoparticles using novel bamboo (Bambusa chungii) leaf extracts. J Nanosci Nanotechnol 15:1674–1677CrossRefGoogle Scholar
  72. Kadiyala NK, Mandal BK, Ranjan S, Dasgupta N (2018) Bioinspired gold nanoparticles decorated reduced graphene oxide nanocomposite using Syzygium cumini seed extract: evaluation of its biological applications. Mater Sci Eng C 93:191–205CrossRefGoogle Scholar
  73. Kahrilas GA et al (2014) Investigation of antibacterial activity by silver nanoparticles prepared by microwave-assisted green syntheses with soluble starch, dextrose, and arabinose. ACS Sustain Chem Eng 2:590–598CrossRefGoogle Scholar
  74. Kamyshny A, Magdassi S (2014) Conductive nanomaterials for printed electronics. Small 10:3515–3535CrossRefGoogle Scholar
  75. Kang B, Opatz T, Landfester K, Wurm FR (2015) Carbohydrate nanocarriers in biomedical applications: functionalization and construction. Chem Soc Rev 44:8301–8325CrossRefGoogle Scholar
  76. Karwa AS, Gaikwad S, Rai MK (2011) Mycosynthesis of silver nanoparticles using Lingzhi or Reishi medicinal mushroom, Ganoderma lucidum (W. Curt.: Fr.) P. Karst. and their role as antimicrobials and antibiotic activity enhancers. Int J Med Mushrooms 13:483–491CrossRefGoogle Scholar
  77. Kasthuri J, Veerapandian S, Rajendiran N (2009) Biological synthesis of silver and gold nanoparticles using apiin as reducing agent. Colloids Surf B: Biointerfaces 68:55–60CrossRefGoogle Scholar
  78. Kharissova OV, Dias HR, Kharisov BI, Pérez BO, Pérez VMJ (2013) The greener synthesis of nanoparticles. Trends Biotechnol 31:240–248CrossRefGoogle Scholar
  79. Khatami M, Nejad MS, Salari S, Almani PGN (2016) Plant-mediated green synthesis of silver nanoparticles using Trifolium resupinatum seed exudate and their antifungal efficacy on Neofusicoccum parvum and Rhizoctonia solani. IET Nanobiotechnol 10:237–243CrossRefGoogle Scholar
  80. Kirthi AV et al (2011) Biosynthesis of titanium dioxide nanoparticles using bacterium Bacillus subtilis. Mater Lett 65:2745–2747CrossRefGoogle Scholar
  81. Kitching M, Ramani M, Marsili E (2015) Fungal biosynthesis of gold nanoparticles: mechanism and scale up. Microb Biotechnol 8:904–917CrossRefGoogle Scholar
  82. Kora AJ, Sashidhar R (2014) Biogenic silver nanoparticles synthesized with rhamnogalacturonan gum: antibacterial activity, cytotoxicity and its mode of action. Arab J ChemGoogle Scholar
  83. Korsvik C, Patil S, Seal S, Self WT (2007) Superoxide dismutase mimetic properties exhibited by vacancy engineered ceria nanoparticles. Chem Commun:1056–1058Google Scholar
  84. Kowshik M, Deshmukh N, Vogel W, Urban J, Kulkarni SK, Paknikar K (2002) Microbial synthesis of semiconductor CdS nanoparticles, their characterization, and their use in the fabrication of an ideal diode. Biotechnol Bioeng 78:583–588CrossRefGoogle Scholar
  85. Kulkarni N, Muddapur U (2014) Biosynthesis of metal nanoparticles: a review. J Nanotechnol 2014Google Scholar
  86. Kumar V, Yadav SK (2009) Plant-mediated synthesis of silver and gold nanoparticles and their applications. J Chem Technol Biotechnol 84:151–157CrossRefGoogle Scholar
  87. Kumar SA, Abyaneh MK, Gosavi S, Kulkarni SK, Pasricha R, Ahmad A, Khan M (2007) Nitrate reductase-mediated synthesis of silver nanoparticles from AgNO3. Biotechnol Lett 29:439–445CrossRefGoogle Scholar
  88. Kumar PSM, Francis AP, Devasena T (2014a) Biosynthesized and chemically synthesized titania nanoparticles: comparative analysis of antibacterial activity. J Environ Nanotechnol 3:73–81Google Scholar
  89. Kumar PV, Pammi S, Kollu P, Satyanarayana K, Shameem U (2014b) Green synthesis and characterization of silver nanoparticles using Boerhaavia diffusa plant extract and their anti bacterial activity. Ind Crop Prod 52:562–566CrossRefGoogle Scholar
  90. Kumar B, Smita K, Cumbal L, Debut A (2017) Extracellular biofabrication of gold nanoparticles by using Lantana camara berry extract. Inorg Nano-Metal Chem 47:138–142CrossRefGoogle Scholar
  91. Lateef A, Adelere I, Gueguim-Kana E, Asafa T, Beukes L (2015) Green synthesis of silver nanoparticles using keratinase obtained from a strain of Bacillus safensis LAU 13. Int Nano Lett 5:29–35CrossRefGoogle Scholar
  92. Lee K, Nagajyothi P, Sreekanth T, Park S (2015) Eco-friendly synthesis of gold nanoparticles (AuNPs) using Inonotus obliquus and their antibacterial, antioxidant and cytotoxic activities. J Ind Eng Chem 26:67–72CrossRefGoogle Scholar
  93. Li S, Shen Y, Xie A, Yu X, Qiu L, Zhang L, Zhang Q (2007) Green synthesis of silver nanoparticles using Capsicum annuum L. extract. Green Chem 9:852–858CrossRefGoogle Scholar
  94. Li C, Li D, Wan G, Xu J, Hou W (2011) Facile synthesis of concentrated gold nanoparticles with low size-distribution in water: temperature and pH controls. Nanoscale Res Lett 6:440CrossRefGoogle Scholar
  95. Llevot A, Dannecker PK, von Czapiewski M, Over LC, Söyler Z, Meier MA (2016) Renewability is not enough: recent advances in the sustainable synthesis of biomass-derived monomers and polymers. Chem Eur J 22:11510–11521CrossRefGoogle Scholar
  96. Maddinedi S b, Mandal BK, Patil SH, Andhalkar VV, Ranjan S, Dasgupta N (2017) Diastase induced green synthesis of bilayered reduced graphene oxide and its decoration with gold nanoparticles. J Photochem Photobiol B Biol 166:252–258CrossRefGoogle Scholar
  97. Makarov V, Love A, Sinitsyna O, Makarova S, Yaminsky I, Taliansky M, Kalinina N (2014) “Green” nanotechnologies: synthesis of metal nanoparticles using plants. Acta Naturae (англоязычная версия) 6:35Google Scholar
  98. Mariselvam R, Ranjitsingh A, Nanthini AUR, Kalirajan K, Padmalatha C, Selvakumar PM (2014) Green synthesis of silver nanoparticles from the extract of the inflorescence of Cocos nucifera (family: Arecaceae) for enhanced antibacterial activity. Spectrochim Acta A Mol Biomol Spectrosc 129:537–541CrossRefGoogle Scholar
  99. Mazumder JA, Ahmad R, Sardar M (2016) Reusable magnetic nanobiocatalyst for synthesis of silver and gold nanoparticles. Int J Biol Macromol 93:66–74CrossRefGoogle Scholar
  100. Mishra A, Sardar M (2012) Alpha-amylase mediated synthesis of silver nanoparticles. Sci Adv Mater 4:143–146CrossRefGoogle Scholar
  101. Mishra A, Sardar M (2014) Alpha amylase mediated synthesis of gold nanoparticles and their application in the reduction of nitroaromatic pollutants. Energy Environ Focus 3:179–184CrossRefGoogle Scholar
  102. Mishra A, Sardar M (2015) Cellulase assisted synthesis of nano-silver and gold: application as immobilization matrix for biocatalysis. Int J Biol Macromol 77:105–113CrossRefGoogle Scholar
  103. Mishra A, Singh P, Sardar M (2015) Peroxidase assisted biosynthesis of silver and gold nanoparticles: characterization and computational study. Adv Mater Lett 6:194CrossRefGoogle Scholar
  104. Mishra P et al (2016) Facile bio-synthesis of gold nanoparticles by using extract of Hibiscus sabdariffa and evaluation of its cytotoxicity against U87 glioblastoma cells under hyperglycemic condition. Biochem Eng J 105:264–272CrossRefGoogle Scholar
  105. Mittal AK, Chisti Y, Banerjee UC (2013) Synthesis of metallic nanoparticles using plant extracts. Biotechnol Adv 31:346–356CrossRefGoogle Scholar
  106. Mochochoko T, Oluwafemi OS, Jumbam DN, Songca SP (2013) Green synthesis of silver nanoparticles using cellulose extracted from an aquatic weed; water hyacinth. Carbohydr Polym 98:290–294CrossRefGoogle Scholar
  107. Mohanpuria P, Rana NK, Yadav SK (2008) Biosynthesis of nanoparticles: technological concepts and future applications. J Nanopart Res 10:507–517CrossRefGoogle Scholar
  108. Mukherjee P et al (2001) Bioreduction of AuCl4− ions by the fungus, Verticillium sp. and surface trapping of the gold nanoparticles formed. Angew Chem Int Ed 40:3585–3588CrossRefGoogle Scholar
  109. Naik RR, Stringer SJ, Agarwal G, Jones SE, Stone MO (2002) Biomimetic synthesis and patterning of silver nanoparticles. Nat Mater 1:169–172CrossRefGoogle Scholar
  110. Nair B, Pradeep T (2002) Coalescence of nanoclusters and formation of submicron crystallites assisted by Lactobacillus strains. Cryst Growth Des 2:293–298CrossRefGoogle Scholar
  111. Namvar F, Azizi S, Ahmad MB, Shameli K, Mohamad R, Mahdavi M, Tahir PM (2015) Green synthesis and characterization of gold nanoparticles using the marine macroalgae Sargassum muticum. Res Chem Intermed 41:5723–5730CrossRefGoogle Scholar
  112. Navrotsky A (2003) Energetics of nanoparticle oxides: interplay between surface energy and polymorphism. Geochem Trans 4:34–37CrossRefGoogle Scholar
  113. Nelson WM (2003) Green solvents for chemistry: perspectives and practice. Oxford University Press, OxfordGoogle Scholar
  114. Newman DK, Kolter R (2000) A role for excreted quinones in extracellular electron transfer. Nature 405:94–97CrossRefGoogle Scholar
  115. Nisbet E, Weiss R (2010) Top-down versus bottom-up. Science 328:1241–1243CrossRefGoogle Scholar
  116. Padil VVT, Černík M (2013) Green synthesis of copper oxide nanoparticles using gum karaya as a biotemplate and their antibacterial application. Int J Nanomedicine 8:889Google Scholar
  117. Palza H (2015) Antimicrobial polymers with metal nanoparticles. Int J Mol Sci 16:2099–2116CrossRefGoogle Scholar
  118. Parida UK, Bindhani BK, Nayak P (2011) Green synthesis and characterization of gold nanoparticles using onion (Allium cepa) extract. World J Nano Sci Eng 1:93–98CrossRefGoogle Scholar
  119. Phanjom P, Zoremi E, Mazumder J, Saha M, Baruah SB (2012) Green synthesis of silver nanoparticles using leaf extract of Myrica esculenta. Int J NanoSci Nanotechnol 3:73–79Google Scholar
  120. Prabhu S, Poulose EK (2012) Silver nanoparticles: mechanism of antimicrobial action, synthesis, medical applications, and toxicity effects. Int Nano Lett 2:32CrossRefGoogle Scholar
  121. Pricker SP (1996) Medical uses of gold compounds: past, present and future. Gold Bull 29:53–60CrossRefGoogle Scholar
  122. Qu J, Yuan X, Wang X, Shao P (2011) Zinc accumulation and synthesis of ZnO nanoparticles using Physalis alkekengi L. Environ Pollut 159:1783–1788CrossRefGoogle Scholar
  123. Rajakumar G et al (2016) Biosynthesis and biomedical applications of gold nanoparticles using Eclipta prostrata leaf extract. Appl Sci 6:222CrossRefGoogle Scholar
  124. Rajan A, Rajan AR, Philip D (2017) Elettaria cardamomum seed mediated rapid synthesis of gold nanoparticles and its biological activities. OpenNano 2:1–8CrossRefGoogle Scholar
  125. Rangnekar A, Sarma TK, Singh AK, Deka J, Ramesh A, Chattopadhyay A (2007) Retention of enzymatic activity of α-amylase in the reductive synthesis of gold nanoparticles. Langmuir 23:5700–5706CrossRefGoogle Scholar
  126. Ranjan S, Dasgupta N, Chakraborty AR, Melvin Samuel S, Ramalingam C, Shanker R, Kumar A (2014) Nanoscience and nanotechnologies in food industries: opportunities and research trends. J Nanopart Res 16(6)Google Scholar
  127. Rasmussen JW, Martinez E, Louka P, Wingett DG (2010) Zinc oxide nanoparticles for selective destruction of tumor cells and potential for drug delivery applications. Expert Opin Drug Deliv 7:1063–1077CrossRefGoogle Scholar
  128. Raveendran P, Fu J, Wallen SL (2003) Completely “green” synthesis and stabilization of metal nanoparticles. J Am Chem Soc 125:13940–13941CrossRefGoogle Scholar
  129. Ravindra P (2009) Protein-mediated synthesis of gold nanoparticles. Mater Sci Eng B 163:93–98CrossRefGoogle Scholar
  130. Ray S, Das AK, Banerjee A (2006) Smart oligopeptide gels: in situ formation and stabilization of gold and silver nanoparticles within supramolecular organogel networks. Chem Commun:2816–2818Google Scholar
  131. Rosoff M (2001) Nano-surface chemistry. CRC Press, Boca RatonCrossRefGoogle Scholar
  132. Sabir S, Arshad M, Chaudhari SK (2014) Zinc oxide nanoparticles for revolutionizing agriculture: synthesis and applications. Sci World J:2014Google Scholar
  133. Santhanam V (2015) Scalable synthesis of noble metal nanoparticles. In: Nanoscale and microscale phenomena. Springer, New Delhi, pp 59–81CrossRefGoogle Scholar
  134. Santos SA, Pinto RJ, Rocha SM, Marques PA, Neto CP, Silvestre AJ, Freire CS (2014) Unveiling the chemistry behind the green synthesis of metal nanoparticles. ChemSusChem 7:2704–2711CrossRefGoogle Scholar
  135. Sastry M, Ahmad A, Khan MI, Kumar R (2003) Biosynthesis of metal nanoparticles using fungi and actinomycete. Curr Sci 85:162–170Google Scholar
  136. Sathishkumar M, Sneha K, Yun Y (2009) Palladium nanocrystal synthesis using Curcuma longa tuber extract. Int J Mater Sci 4:11–17Google Scholar
  137. Satishkumar M, Sneha K, Won S, Cho C, Kim S, Yun Y (2009) Cinnamon zeylanicum bark extract and powder mediated green synthesis of nano-crystalline silver particles and its antibacterial activity. Colloids Surf B: Biointerface 73:332–338CrossRefGoogle Scholar
  138. Schabes-Retchkiman P, Canizal G, Herrera-Becerra R, Zorrilla C, Liu H, Ascencio J (2006) Biosynthesis and characterization of Ti/Ni bimetallic nanoparticles. Opt Mater 29:95–99CrossRefGoogle Scholar
  139. Shabestarian H, Homayouni-Tabrizi M, Soltani M, Namvar F, Azizi S, Mohamad R, Shabestarian H (2016) Green synthesis of gold nanoparticles using sumac aqueous extract and their antioxidant activity. Mater Res 20:264CrossRefGoogle Scholar
  140. Shankar SS, Ahmad A, Sastry M (2003) Geranium leaf assisted biosynthesis of silver nanoparticles. Biotechnol Prog 19:1627–1631CrossRefGoogle Scholar
  141. Shankar SS, Rai A, Ahmad A, Sastry M (2005) Controlling the optical properties of lemongrass extract synthesized gold nanotriangles and potential application in infrared-absorbing optical coatings. Chem Mater 17:566–572CrossRefGoogle Scholar
  142. Shi J, Votruba AR, Farokhzad OC, Langer R (2010) Nanotechnology in drug delivery and tissue engineering: from discovery to applications. Nano Lett 10:3223–3230CrossRefGoogle Scholar
  143. Singaravelu G, Arockiamary J, Kumar VG, Govindaraju K (2007) A novel extracellular synthesis of monodisperse gold nanoparticles using marine alga, Sargassum wightii Greville. Colloids Surf B: Biointerfaces 57:97–101CrossRefGoogle Scholar
  144. Singh AV, Bandgar BM, Kasture M, Prasad B, Sastry M (2005) Synthesis of gold, silver and their alloy nanoparticles using bovine serum albumin as foaming and stabilizing agent. J Mater Chem 15:5115–5121CrossRefGoogle Scholar
  145. Singh P, Kim YJ, Yang DC (2016) A strategic approach for rapid synthesis of gold and silver nanoparticles by Panax ginseng leaves. Artif Cells Nanomed Biotechnol 44:1949–1957CrossRefGoogle Scholar
  146. Sivakumar J, Premkumar C, Santhanam P, Saraswathi N (2011) Biosynthesis of silver nanoparticles using Calotropis gigantean leaf. Afr J Basic Appl Sci 3:265–270Google Scholar
  147. Soenen SJ, Parak WJ, Rejman J, Manshian B (2015) (Intra) cellular stability of inorganic nanoparticles: effects on cytotoxicity, particle functionality, and biomedical applications. Chem Rev 115:2109–2135CrossRefGoogle Scholar
  148. Song JY, Kwon E-Y, Kim BS (2010) Biological synthesis of platinum nanoparticles using Diopyros kaki leaf extract. Bioprocess Biosyst Eng 33:159–164CrossRefGoogle Scholar
  149. Soundarrajan C, Sankari A, Dhandapani P, Maruthamuthu S, Ravichandran S, Sozhan G, Palaniswamy N (2012) Rapid biological synthesis of platinum nanoparticles using Ocimum sanctum for water electrolysis applications. Bioprocess Biosyst Eng 35:827–833CrossRefGoogle Scholar
  150. Sowani H et al (2016) Green synthesis of gold and silver nanoparticles by an actinomycete Gordonia amicalis HS-11: mechanistic aspects and biological application. Process Biochem 51:374–383CrossRefGoogle Scholar
  151. Stone V et al (2010) Nanomaterials for environmental studies: classification, reference material issues, and strategies for physico-chemical characterisation. Sci Total Environ 408:1745–1754CrossRefGoogle Scholar
  152. Suzuki Y, Kitatsuji Y, Ohnuki T, Tsujimura S (2010) Flavin mononucleotide mediated electron pathway for microbial U (VI) reduction. Phys Chem Chem Phys 12:10081–10087CrossRefGoogle Scholar
  153. Takeda Y, Mae S, Kajikawa Y, Matsushima K (2009) Nanobiotechnology as an emerging research domain from nanotechnology: a bibliometric approach. Scientometrics 80:23–38CrossRefGoogle Scholar
  154. Talekar S et al (2014) Preparation of stable cross-linked enzyme aggregates (CLEAs) of NADH-dependent nitrate reductase and its use for silver nanoparticle synthesis from silver nitrate. Catal Commun 53:62–66CrossRefGoogle Scholar
  155. Tammina SK, Mandal BK, Ranjan S, Dasgupta N (2017) Cytotoxicity study of Piper nigrum seed mediated synthesized SnO2 nanoparticles towards colorectal (HCT116) and lung cancer (A549) cell lines. J Photochem Photobiol B Biol 166:158–168CrossRefGoogle Scholar
  156. Tan YN, Lee JY, Wang DI (2010) Uncovering the design rules for peptide synthesis of metal nanoparticles. J Am Chem Soc 132:5677–5686CrossRefGoogle Scholar
  157. Teoh WY, Mädler L, Beydoun D, Pratsinis SE, Amal R (2005) Direct (one-step) synthesis of TiO2 and Pt/TiO2 nanoparticles for photocatalytic mineralisation of sucrose. Chem Eng Sci 60:5852–5861CrossRefGoogle Scholar
  158. Teoh WY, Amal R, Mädler L (2010) Flame spray pyrolysis: an enabling technology for nanoparticles design and fabrication. Nanoscale 2:1324–1347CrossRefGoogle Scholar
  159. Thakkar KN, Mhatre SS, Parikh RY (2010) Biological synthesis of metallic nanoparticles. Nanomedicine 6:257–262CrossRefGoogle Scholar
  160. Tidke PR, Gupta I, Gade AK, Rai M (2014) Fungus-mediated synthesis of gold nanoparticles and standardization of parameters for its biosynthesis. IEEE Trans Nanobioscience 13:397–402CrossRefGoogle Scholar
  161. Tong G, Du F, Xiang L, Liu F, Mao L, Guan J (2014) Generalized green synthesis and formation mechanism of sponge-like ferrite micro-polyhedra with tunable structure and composition. Nanoscale 6:778–787CrossRefGoogle Scholar
  162. Tripathi A, Chandrasekaran N, Raichur A, Mukherjee A (2009) Antibacterial applications of silver nanoparticles synthesized by aqueous extract of Azadirachta indica (Neem) leaves. J Biomed Nanotechnol 5:93–98CrossRefGoogle Scholar
  163. Valdez J, Gómez I (2016) One-step green synthesis of metallic nanoparticles using sodium alginate. J Nanomater 2016:33CrossRefGoogle Scholar
  164. Veerakumar K, Govindarajan M, Rajeswary M, Muthukumaran U (2014) Low-cost and eco-friendly green synthesis of silver nanoparticles using Feronia elephantum (Rutaceae) against Culex quinquefasciatus, Anopheles stephensi, and Aedes aegypti (Diptera: Culicidae). Parasitol Res 113:1775–1785CrossRefGoogle Scholar
  165. Veisi H, Ghorbani-Vaghei R, Hemmati S, Aliani MH, Ozturk T (2015) Green and effective route for the synthesis of monodispersed palladium nanoparticles using herbal tea extract (Stachys lavandulifolia) as reductant, stabilizer and capping agent, and their application as homogeneous and reusable catalyst in Suzuki coupling reactions in water. Appl Organomet Chem 29:26–32CrossRefGoogle Scholar
  166. Venkatesh K, Krishnamoorthi S, Palani N, Thirumal V, Jose SP, Wang F-M, Ilangovan R (2015) Facile one step synthesis of novel TiO2 nanocoral by sol-gel method using Aloe vera plant extract. Indian J Phys 89:445–452CrossRefGoogle Scholar
  167. Venkatesham M, Ayodhya D, Madhusudhan A, Babu NV, Veerabhadram G (2014) A novel green one-step synthesis of silver nanoparticles using chitosan: catalytic activity and antimicrobial studies. Appl Nanosci 4:113–119CrossRefGoogle Scholar
  168. Vigneshwaran N, Nachane R, Balasubramanya R, Varadarajan P (2006) A novel one-pot ‘green’synthesis of stable silver nanoparticles using soluble starch. Carbohydr Res 341:2012–2018CrossRefGoogle Scholar
  169. Vilchis-Nestor AR, Sánchez-Mendieta V, Camacho-López MA, Gómez-Espinosa RM, Camacho-López MA, Arenas-Alatorre JA (2008) Solventless synthesis and optical properties of Au and Ag nanoparticles using Camellia sinensis extract. Mater Lett 62:3103–3105CrossRefGoogle Scholar
  170. Wadhwani SA, Shedbalkar UU, Singh R, Vashisth P, Pruthi V, Chopade BA (2016) Kinetics of synthesis of gold nanoparticles by Acinetobacter sp. SW30 isolated from environment. Indian J Microbiol 56:439–444CrossRefGoogle Scholar
  171. Wang Y, Zeiri O, Neyman A, Stellacci F, Weinstock IA (2011) Nucleation and island growth of alkanethiolate ligand domains on gold nanoparticles. ACS Nano 6:629–640CrossRefGoogle Scholar
  172. Wang T, Lin J, Chen Z, Megharaj M, Naidu R (2014) Green synthesized iron nanoparticles by green tea and eucalyptus leaves extracts used for removal of nitrate in aqueous solution. J Clean Prod 83:413–419CrossRefGoogle Scholar
  173. Wang C, Kim YJ, Singh P, Mathiyalagan R, Jin Y, Yang DC (2016) Green synthesis of silver nanoparticles by Bacillus methylotrophicus, and their antimicrobial activity. Artif Cells Nanomed Biotechnol 44:1127–1132CrossRefGoogle Scholar
  174. Watcharaporn K, Opaprakasit M, Pimpan V (2014) Effects of UV radiation and Ph of tannic acid solution in the synthesis of silver nanoparticles. In: Advanced materials research. Trans Tech Publ, Durnten-Zurich, pp 110–114Google Scholar
  175. Willets KA, Van Duyne RP (2007) Localized surface plasmon resonance spectroscopy and sensing. Annu Rev Phys Chem 58:267–297CrossRefGoogle Scholar
  176. Wing-ShanáLin I (2014) Biosynthesis of silver nanoparticles from silver (i) reduction by the periplasmic nitrate reductase c-type cytochrome subunit NapC in a silver-resistant E. ácoli. Chem Sci 5:3144–3150CrossRefGoogle Scholar
  177. Wu Z, Yang S, Wu W (2016) Shape control of inorganic nanoparticles from solution. Nanoscale 8:1237–1259CrossRefGoogle Scholar
  178. Xiong Y, Xia Y (2007) Shape-controlled synthesis of metal nanostructures: the case of palladium. Adv Mater 19:3385–3391CrossRefGoogle Scholar
  179. Xue B, He D, Gao S, Wang D, Yokoyama K, Wang L (2016) Biosynthesis of silver nanoparticles by the fungus Arthroderma fulvum and its antifungal activity against genera of Candida, Aspergillus and Fusarium. Int J Nanomedicine 11:1899Google Scholar
  180. Yan J-K, Wang Y-Y, Ma H-L (2015) Green synthesis and stabilization of gold nanoparticles via carboxymethylated curdlan. Curr Top Nutraceuticals Res 13:259Google Scholar
  181. Yang X, Luo Y, Zhuo Y, Feng Y, Zhu S (2014) Novel synthesis of gold nanoclusters templated with l-tyrosine for selective analyzing tyrosinase. Anal Chim Acta 840:87–92CrossRefGoogle Scholar
  182. Zhang G et al (2009) Synthesis of various crystalline gold nanostructures in water: the polyoxometalate β-[H 4 PMo 12 O 40] 3− as the reducing and stabilizing agent. J Mater Chem 19:8639–8644CrossRefGoogle Scholar
  183. Zhao F, Yao D, Guo R, Deng L, Dong A, Zhang J (2015) Composites of polymer hydrogels and nanoparticulate systems for biomedical and pharmaceutical applications. Nano 5:2054–2130Google Scholar
  184. Zhou Y et al (2010) Biosynthesis of gold nanoparticles by foliar broths: roles of biocompounds and other attributes of the extracts. Nanoscale Res Lett 5:1351–1359CrossRefGoogle Scholar

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Authors and Affiliations

  1. 1.Department of BiosciencesJamia Millia IslamiaNew DelhiIndia

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