Liver Disease pp 105-115 | Cite as

Liver Disease and Pregnancy

  • Lydia Aye
  • Tram Tran


Recognition of normal and abnormal liver tests and physiology in pregnancy is essential. Rarely does a pregnant woman experience severe liver disease during her pregnancy, but it is important to recognize these patients to reduce morbidity and mortality for the mother and infant. We will discuss liver disease in a pregnant patient and liver diseases unique to pregnancy.


Pregnancy Intrahepatic cholestasis of pregnancy HELLP syndrome Hepatitis E Hepatitis B Acute fatty liver of pregnancy 

Further Reading

  1. 1.
    AASLD/IDSA recommendations for testing, managing, and treating hepatitis C.
  2. 2.
    Brennan PN, Donnelly MC, Simpson KJ. Systematic review: non A-E, seronegative or indeterminate hepatitis; what is this deadly disease? Aliment Pharmacol Ther. 2018;47:1079–91.CrossRefGoogle Scholar
  3. 3.
    CDC morbidity and mortality weekly report.
  4. 4.
    Copel J, El-Sayed Y, Heine RP, Wharton KR. Guidelines for diagnostic imaging during pregnancy and lactations. Obstet Gynecol. 2017;130:e210–6.CrossRefGoogle Scholar
  5. 5.
    Ryan J, Heneghan M. Pregnancy and liver. Clinical Liver Disease. 2014;4:51–4.CrossRefGoogle Scholar
  6. 6.
    Terrault NA, Bzowej NH, Chang KM, Hwant J, Jonas MM, Murad MH. AASLD guidelines for treatment of chronic hepatitis B. Hepatology. 2016;63:261–83.CrossRefGoogle Scholar
  7. 7.
    Tran TT, Ahn J, Reau NS. ACG clinical guidelines: liver disease and pregnancy. Am J Gastroenterol. 2016;111:176–94.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Division of Gastroenterology and HepatologyLoma Linda UniversityLoma LindaUSA
  2. 2.South Bay GastroenterologyTorranceUSA

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