This chapter discusses key distinguishing features of hepatorenal syndrome from other etiologies of kidney injury. The pathophysiology as it is currently understood, as well as best treatment options based on clinical evidence, is described. An emphasis is placed on early diagnosis and treatment. Due to the poor prognosis despite maximal medical therapy, referral for liver transplantation should be initiated.
KeywordsPortal hypertension Ascites Terlipressin Norepinephrine Sympathetic nervous system Vasopressin Renin-angiotensin-aldosterone system
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