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Management of Recurrent Peptic Ulcer Disease

  • Carl J. Dickler
  • Konstantinos SpaniolasEmail author
Chapter

Abstract

The advent of proton pump inhibitors (PPIs) and histamine-2 (H2) blockers has led to a significant decrease in the number of patients who require surgical management of peptic ulcer disease. However, there is still a small subset of patients with pathologies that will lead to recurrent peptic ulcer disease. Understanding these pathologies is critical in allowing clinicians to correctly identify and treat them.

Keywords

PUD Retained antrum Zollinger–Ellison syndrome Pseudo-Zollinger–Ellison syndrome Hypergastrinemia Secretin test Standard meal test Tc-99 scan Octreotide scan Gastrectomy 

Suggested Reading

  1. Cameron JL, Cameron AM. Stomach. In: Current surgical therapy. 11th ed. Philadelphia, PA: Saunders; 2014. p. 69–107.Google Scholar
  2. Dacha S, et al. Hypergastrinemia. Gastroenterol Rep. 2015;3(3):201–8.  https://doi.org/10.1093/gastro/gov004.CrossRefGoogle Scholar
  3. Fisher WE, et al. Pancreas. In: Schwartz’s principles of surgery. New York City, NY: McGraw-Hill Education\Medical; 2015. p. 1392–3.Google Scholar
  4. Gray GR, et al. Extragastric gastrinoma or G-cell hyperplasia of the antrum? The preoperative diagnosis in a case of hypergastrinaemia. Br J Surg. 1976;63(8):596–8.  https://doi.org/10.1002/bjs.1800630809.CrossRefPubMedGoogle Scholar
  5. Keuppens F, et al. Antral gastrin cell hyperplasia in patients with peptic ulcer. Ann Surg. U.S. National Library of Medicine, 1980. www.ncbi.nlm.nih.gov/pubmed/7362294.
  6. Kitagawa Y, Dempsey DT. Stomach. In: Schwartz’s principles of surgery. New York City, NY: McGraw-Hill Education\Medical; 2015. p. 1035–95.Google Scholar
  7. Teitelbaum EN, et al. Stomach. In: Sabiston textbook of surgery: the biological basis of modern surgical practice. 12th ed. Philadephia, PA: Elsevier; 2017. p. 1188–236.Google Scholar
  8. Vakil N. Approach to refractory or recurrent peptic ulcer disease. Approach to refractory or recurrent peptic ulcer disease. UpToDate5, 5 July 2017, www.uptodate.com/contents/approach-to-refractory-or-recurrent-peptic-ulcer-disease.

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of General SurgerySUNY Stony Brook University Hospital, Health Sciences Center T19-030Stony BrookUSA
  2. 2.Department of SurgeryStony Brook University HospitalStony BrookUSA

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