Pancreatic Necrosis

  • Ammar Asrar Javed
  • Matthew J. WeissEmail author


Acute pancreatitis is one of the most common gastrointestinal disorders requiring hospitalization. Approximately 20% of pancreatitis patients will develop pancreatic necrosis, which can lead to a systemic inflammatory response, multi-organ system failure, and death. Early intervention is essential to avoid poor outcomes. Open necrosectomy has historically been the treatment of choice. More recently, a step-up approach has become more common. This chapter discusses this approach, which is depicted in the subsequent algorithm.


Acute pancreatitis Pancreatic necrosis Necrosectomy Step-up approach Algorithm 


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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of SurgeryJohns Hopkins HospitalBaltimoreUSA

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