Benign Cystic Lesions
Several types of benign cysts occur in parenchymal, ventricular, or subarachnoid space locations throughout the cranial and spinal cavities. They can be classified according to their cell lining into epithelial-lining cysts (squamous and columnar-to-cuboidal) and nonepithelial-lining cysts (arachnoid membrane and astrocytic gliosis). Their differential diagnosis depends largely on their location, as well as on the lining cells (when intact) and cystic content. This chapter reviews the cytomorphologic features and differential diagnosis of these entities.
KeywordsIntraoperative brain assessment Cytology Squash preparation Smear preparation Benign cysts Benign cystic lesions Epidermoid cyst Dermoid cyst Colloid cyst Rathke cleft cyst Endodermal cyst Enterogenous cyst Ependymal cyst Choroid plexus cyst Arachnoid cyst Glial cyst Simple cyst Pineal cyst
- Akhaddar A, Mahi M, Amarti A, el Quessar A, et al. Simple cyst of the cerebellum. Report of a case. J Neuropathol. 2001;28:209–14.Google Scholar
- Bilguvar K, Ozturk AK, Bayrakli F, Guzel A, et al. The syndrome of pachygyria, mental retardation, and arachnoid cysts maps to 11p15. Am J Med Genet. 2009;149:2369–572.Google Scholar
- Burger PC, Scheithauer BW. Benign cystic lesions. In: Tumors of the central nervous system. AFIP atlas of tumor pathology. Series 4. Washington DC: ARP Press; 2007. p. 471–90.Google Scholar
- Fuller GN, Ballester LY, Perry A. Cysts of the central nervous system. In: Perry A, Brat DJ, editors. Practical surgical neuropathology. A diagnostic approach. Philadelphia: Elsevier; 2018. p. 393–404.Google Scholar
- Oprişan A, Popescu BO. Intracranial cysts: an imagery diagnostic challenge. Scientific World J. 2013;2:172154.Google Scholar