Benign Cystic Lesions

  • César R. Lacruz
  • Javier Saénz de Santamaría
  • Ricardo H. Bardales
Part of the Essentials in Cytopathology book series (EICP, volume 13)


Several types of benign cysts occur in parenchymal, ventricular, or subarachnoid space locations throughout the cranial and spinal cavities. They can be classified according to their cell lining into epithelial-lining cysts (squamous and columnar-to-cuboidal) and nonepithelial-lining cysts (arachnoid membrane and astrocytic gliosis). Their differential diagnosis depends largely on their location, as well as on the lining cells (when intact) and cystic content. This chapter reviews the cytomorphologic features and differential diagnosis of these entities.


Intraoperative brain assessment Cytology Squash preparation Smear preparation Benign cysts Benign cystic lesions Epidermoid cyst Dermoid cyst Colloid cyst Rathke cleft cyst Endodermal cyst Enterogenous cyst Ependymal cyst Choroid plexus cyst Arachnoid cyst Glial cyst Simple cyst Pineal cyst 

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Copyright information

© Springer Nature Switzerland AG 2018

Authors and Affiliations

  • César R. Lacruz
    • 1
  • Javier Saénz de Santamaría
    • 2
  • Ricardo H. Bardales
    • 3
  1. 1.Professor of PathologyComplutense University School of MedicineMadridSpain
  2. 2.Professor of PathologyUniversity Hospital Extremadura, Medical SchoolBadajozSpain
  3. 3.Pathologist, Director Ultrasound-guided Fine Needle Aspiration ServiceOutpatient Pathology Associates / Precision PathologySacramentoUSA

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