Nerve Sheath Tumors of the Craniospinal Axis
A large number of neurosurgical specimens originate outside of the central neuraxis proper from the nerve sheath cells of the cranial and spinal nerve roots, the vast majority of which are schwannomas arising in the posterior fossa and spinal canal. Specimens from this tumor are difficult to crush yielding smears with cohesive tissue fragments and few, if any, single cells. This chapter also includes the cytomorphologic features and differential diagnosis of melanotic schwannoma, neurofibroma, malignant peripheral nerve sheath tumor, and ganglioneuroma.
KeywordsIntraoperative brain assessment Cytology Squash technique Smear technique Schwannoma Cellular schwannoma Melanotic schwannoma Neurofibroma MPNST Ganglioneuroma Neurofibromatosis type 1 Neurofibromatosis type 2 Schwannomatosis Carney complex
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