• Samata Singhi
  • Erin Steinhart
  • Kiran MaskiEmail author


Hypersomnia is characterized by irrepressible need for sleep resulting in excessive daytime sleepiness. The diagnosis of hypersomnia assumes that a patient is receiving a sufficient amount of regular nocturnal sleep. While hypersomnia is a relatively rare condition, it has been described in disorders such as primary depression, attention-deficit/hyperactivity disorder, and neurogenetic conditions. Narcolepsy, idiopathic hypersomnia, and Kleine-Levin syndrome represent primary central nervous system disorders characterized by hypersomnia. Narcolepsy in particular can also be associated with neurobehavioral and mood disorders making diagnosis and management complicated. In this chapter, we review primary and secondary causes of hypersomnia, detail clinical diagnostic tools, and discuss commonly used treatments for hypersomnia.


Hypersomnia Excessive daytime sleepiness Narcolepsy ADHD Depression Kleine-Levine syndrome Idiopathic hypersomnia Prader-Willi syndrome Smith-Magenis syndrome Polysomnography Multiple sleep latency testing Stimulants Modafinil Sodium oxybate 


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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of NeurologyBoston Children’s HospitalBostonUSA
  2. 2.Clinical Research Operations, Department of NeurologyBoston Children’s HospitalBostonUSA
  3. 3.Harvard Medical SchoolBostonUSA

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