Advertisement

What Is Dumping Syndrome? How Do I Diagnose and Treat Dumping Syndrome?

  • Zhaoxin Yang
  • Autumn Graham
Chapter

Abstract

Dumping syndrome refers to a constellation of symptoms that occurs when food reaches the small bowel too rapidly. Symptoms are triggered by meals, and there are both early symptoms as well as late findings. In the acute care setting, diagnosis is based on symptoms in relationship to oral intake. Definitive diagnosis is made with a modified oral glucose tolerance test that can be done as an outpatient. The initial dumping syndrome management relies on dietary modifications. After dietary modifications, medications such as somatostatin analogs (e.g. octreotide) are the next step which delay gastric emptying and small bowel transit time, as well as inhibit gastric hormones and insulin secretion.

Keywords

Dumping syndrome Abdominal pain Bariatric surgery Gastric bypass 

References

  1. 1.
    Tack J. Pathophysiology, diagnosis and management of postoperative dumping syndrome. Nat Rev Gastroenterol Hepatol. 2009;6:583–90.CrossRefGoogle Scholar
  2. 2.
    Tack J. Gastric motor disorders. Best Pract Res Clin Gastroenterol. 2007;21:633–44.CrossRefGoogle Scholar
  3. 3.
    Sigstad H. A clinical diagnostic index in the diagnosis of the dumping syndrome. Changes in plasma volume and blood sugar after a test meal. Acta Med Scandinavica. 1970;188:479–86.CrossRefGoogle Scholar
  4. 4.
    Service G. Hyperinsulinemic hypoglycemia with nesidioblastosis after gastric-bypass surgery. N Engl J Med. 2005;353:249–54.CrossRefGoogle Scholar
  5. 5.
    Laurenius A. Dumping syndrome following gastric bypass: validation of the dumping syndrome rating scale. Obes Surg. 2013;23:740–55.CrossRefGoogle Scholar
  6. 6.
    Van der Kleij F, Vecht J, Lamers C, Masclee AA. Diagnostic value of dumping provocation in patients after gastric surgery. Scand J Gastroenterol. 1996;31:1162–6.CrossRefGoogle Scholar
  7. 7.
    Vecht J, Masclee A, Lamers C. The dumping syndrome: current insights into pathophysiology, diagnosis and treatment. Scand J Gastroenterol. 1997;223:21–7.Google Scholar
  8. 8.
    Abell T, Minocha A. Gastrointestinal complications of bariatric surgery: diagnosis and therapy. Am J Med Sci. 2006;331:214–8.CrossRefGoogle Scholar
  9. 9.
    Harju E, Larmi T. Efficacy of guar gum in preventing the dumping syndrome. JPEN. 1983;7:470–2.CrossRefGoogle Scholar
  10. 10.
    Lyons T, McLoughlin J, Shaw C, Buchanan K. Effect of acarbose on biochemical responses and clinical symptoms in dumping syndrome. Digestion. 1985;31:89–96.CrossRefGoogle Scholar
  11. 11.
    Arts J. Efficacy of the long-acting repeatable formulation of the somatostatin analog octreotide in postoperative dumping. Clin Gastroenterol Hepatol. 2009;7:432–7.CrossRefGoogle Scholar
  12. 12.
    Geer R. Efficacy of octreotide acetate in treatment of severe post-gastrectomy dumping syndrome. Ann Surg. 1990;212:678–87.CrossRefGoogle Scholar
  13. 13.
    Woodward E, Deser P, Gasster M. Surgical treatment of the post-gastrectomy dumping syndrome. West J Surg Obstet Gynecol. 1955;63:567–73.PubMedGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Zhaoxin Yang
    • 1
  • Autumn Graham
    • 2
  1. 1.MedStar Georgetown University Hospital, Department of Emergency MedicineWashington, DCUSA
  2. 2.Department of Emergency MedicineMedStar Washington Hospital Center, MedStar Georgetown University HospitalWashington, DCUSA

Personalised recommendations