Dielectric Modulated AlGaAs/GaAs HEMT for Label Free Detection of Biomolecules

  • R. K. Paswan
  • D. K. Panda
  • T. R. LenkaEmail author
Conference paper
Part of the Springer Proceedings in Physics book series (SPPHY, volume 215)


This paper presents a dielectric modulated high electron mobility transistor (HEMT) for label free detection of biomolecules. For analysis of biomolecules, an immobilization site has been created at the gate by carving a nano-gap in the gate oxide. This carved nano-gap acts as the binding site for biomolecules and changes the dielectric behavior of the gate oxide hence changing the characteristics of the proposed structure. The sensing parameter used is the threshold voltage which showed variation after application of immobilized biomolecules at the binding site. Simulation has been carried out for neutral and charged biomolecules using Silvaco TCAD.



The authors acknowledge TEQIP-II for facilitating Silvaco TCAD tool in Department of ECE, NIT Silchar for carrying out the research work.


  1. 1.
    C.S. Lee, S. Kyu Kim, M. Kim, Ion-sensitive field-effect transistor for biological sensing. Sensors 9(9), 7111–7131 (2009)CrossRefGoogle Scholar
  2. 2.
    H. Im, X.-J. Huang, B. Gu, Y.-K. Choi, A dielectric-modulated field-effect transistor for biosensing. Nat. Nanotechnol. 2(7), 430–434 (2007)ADSCrossRefGoogle Scholar
  3. 3.
    D. Moon, J. Han, S. Member, M. Meyyappan, Comparative study of field effect transistor based biosensors. IEEE Trans. Nanotechnol. 15(6), 956–961 (2016)ADSCrossRefGoogle Scholar
  4. 4.
    R.N. Ajay, M. Saxena, M. Gupta, Drain current model of a four-gate dielectric modulated MOSFET for application as a biosensor. IEEE Trans. Electron Devices 62(8), 2636–2644 (2015)ADSCrossRefGoogle Scholar
  5. 5.
    A.P. Huang, Z.C. Yang, P.K. Chu, Hafnium-based high-k gate dielectrics, in Advances in Solid State Circuits Technologies, pp. 333–350 (2010)Google Scholar
  6. 6.
    R. Pethig, Dielectric properties of biological materials: biophysical and medical applications. IEEE Trans. Electr. Insul. EI-19(5), 453–474 (1984)CrossRefGoogle Scholar
  7. 7.
    J.W. Pitera, M. Falta, W.F. van Gunsteren, Dielectric properties of proteins from simulation: the effects of solvent, ligands, pH, and temperature. Biophys. J. 80(6), 2546–2555 (2001)CrossRefGoogle Scholar
  8. 8.
    P. Bergveld, The development and application of FET-based biosensors. Biosens. Els. Appl. Sci. 2(1), 15–33 (1986)Google Scholar
  9. 9.
    R.N. Ajay, M. Saxena, M. Gupta, Analytical modeling of a split-gate dielectric modulated metal-oxide-semiconductor field-effect transistor for application as a biosensor, in Proceedings of the IEEE International Caracas Conference on Devices, Circuits and Systems, ICCDCS, pp. 1–6 (2014)Google Scholar
  10. 10.
    S. Gs, A. Cv, B.B. Mathew, Biosensors: a modern day achievement. J. Instrum. Technol. 2(1), 26–39 (2014)Google Scholar
  11. 11.
    A. Syahir, K. Usui, K. Tomizaki, K. Kajikawa, H. Mihara, Label and label-free detection techniques for protein microarrays. Microarrays 4(2), 228–244 (2015)CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Microelectronics and VLSI Design Group, Department of Electronics and Communication EngineeringNational Institute of Technology SilcharAssamIndia

Personalised recommendations