Advertisement

Genomics of Fungal Disease Resistance

  • Randall J. WisserEmail author
  • Nick Lauter
Chapter
Part of the Compendium of Plant Genomes book series (CPG)

Abstract

Fungal diseases are prevalent on maize, for which resistance is controlled by numerous genes where sequence variation more typically gives rise to quantitative rather than qualitative phenotypes. Genomics is facilitating advances in genetics and systems biology while opening the door for convergence between the two. As this is leading to new perspectives about the nature of functionality versus variability during pathogenesis, changes may be afoot in how maize breeders handle the challenge of crop protection.

Keywords

Allele mining Genetic architecture Genomic selection Systems biology Pathogenesis Fungi Maize 

Notes

Acknowledgements

This work was made possible by the US NSF Plant Genome Research Program IOS-1127076 and the US Department of Agriculture—Agricultural Research Service.

References

  1. Balint-Kurti PJ, Zwonitzer JC, Wisser RJ et al (2007) Precise mapping of quantitative trait loci for resistance to southern leaf blight, caused by Cochliobolus heterostrophus race O, and flowering time using advanced intercross maize lines. Genetics 176:645–657CrossRefGoogle Scholar
  2. Barrangou R, Horvath P (2017) A decade of discovery: CRISPR functions and applications. Nat Microbiol 2:1–9CrossRefGoogle Scholar
  3. Beavis WD (1997) QTL analysis, power, precision, and accuracy. In: Paterson A (ed) Molecular dissection of complex traits. CRC Press, New York, pp 145–162Google Scholar
  4. Bennetzen JL, Qin M-M, Ingels S, Ellingboe AH (1988) Allele-specific and mutator-associated instability at the Rp1 disease-resistance locus of maize. Nature 332:369–370CrossRefGoogle Scholar
  5. Benson JM, Poland JA, Benson BM et al (2015) Resistance to gray leaf spot of maize: genetic architecture and mechanisms elucidated through nested association mapping and near-isogenic line analysis. PLoS Genet 11:1–23CrossRefGoogle Scholar
  6. Borrego E, Kolomiets M (2016) Synthesis and functions of jasmonates in maize. Plants 5(4):E41CrossRefGoogle Scholar
  7. Brosch G, Ransom R, Lechner T et al (1995) Inhibition of maize histone deacetylases by HC toxin, the host-selective toxin of Cochliobolus carbonum. Plant Cell 7:1941–1950CrossRefGoogle Scholar
  8. Choudhary C, Kumar C, Gnad F et al (2009) Lysine acetylation targets protein complexes and co-regulated major cellular functions. Science 325:834–840CrossRefGoogle Scholar
  9. Christensen SA, Huffaker A, Kaplan F et al (2015) Maize death acids, 9-lipoxygenase–derived cyclopente(a)nones, display activity as cytotoxic phytoalexins and transcriptional mediators. Proc Natl Acad Sci 112:11407–11412CrossRefGoogle Scholar
  10. Christensen SA, Kolomiets MV (2011) The lipid language of plant-fungal interactions. Fungal Genet Biol 48:4–14CrossRefGoogle Scholar
  11. Christensen SA, Nemchenko A, Park Y-S et al (2014) The novel monocot-specific 9-lipoxygenase ZmLOX12 is required to mount an effective jasmonate-mediated defense against Fusarium verticillioides in maize. Mol Plant-Microbe Interact 27:1263–1276CrossRefGoogle Scholar
  12. Christensen SA, Sims J, Vaughan MM et al (2018) Commercial hybrids and mutant genotypes reveal complex protective roles for inducible terpenoid defenses in maize. J Exp Bot 69:1693–1705CrossRefGoogle Scholar
  13. Christie N, Myburg AA, Joubert F et al (2017) Systems genetics reveals a transcriptional network associated with susceptibility in the maize–grey leaf spot pathosystem. Plant J 89:746–763CrossRefGoogle Scholar
  14. Corwin JA, Kliebenstein DJ (2017) Quantitative resistance: more than just perception of a pathogen. Plant Cell 29:655–665CrossRefGoogle Scholar
  15. dos Santos JPR, Pires LPM, de Castro Vasconcellos RC et al (2016) Genomic selection to resistance to Stenocarpella maydis in maize lines using DArTseq markers. BMC Genet 17:1–10CrossRefGoogle Scholar
  16. French E, Kim BS, Iyer-Pascuzzi AS (2016) Mechanisms of quantitative disease resistance in plants. Semin Cell Dev Biol 56:201–208CrossRefGoogle Scholar
  17. Gross ML, McCrery D, Crow F et al (1982) The structure of the toxin from helminthosporium carbonum. Tetrahedron Lett 23:5381–5384CrossRefGoogle Scholar
  18. Han S, Utz HF, Liu W et al (2016) Choice of models for QTL mapping with multiple families and design of the training set for prediction of Fusarium resistance traits in maize. Theor Appl Genet 129:431–444CrossRefGoogle Scholar
  19. Hansen BG, Halkier BA, Kliebenstein DJ (2008) Identifying the molecular basis of QTLs: eQTLs add a new dimension. Trends Plant Sci 13:72–77CrossRefGoogle Scholar
  20. Huffaker A, Kaplan F, Vaughan MM et al (2011) Novel acidic sesquiterpenoids constitute a dominant class of pathogen-induced phytoalexins in maize. Plant Physiol 156:2082–2097CrossRefGoogle Scholar
  21. Johal GS, Briggs SP (1992) Reductase activity encoded by the HM1 disease resistance gene in maize. Science 258:985–987CrossRefGoogle Scholar
  22. Johnson R (1983) Genetic background of durable resistance. Durable resistance in crops. Springer, New York, pp 5–26CrossRefGoogle Scholar
  23. Kou Y, Wang S (2010) Broad-spectrum and durability: understanding of quantitative disease resistance. Curr Opin Plant Biol 13:181–185CrossRefGoogle Scholar
  24. Krauz JP, Fredericksen RA, Rodrigues-Ballesteros OR (1993) Epidemic of northern corn leaf blight in Texas in 1992. Plant Disease 77:1063CrossRefGoogle Scholar
  25. Kump KL, Bradbury PJ, Wisser RJ et al (2011) Genome-wide association study of quantitative resistance to southern leaf blight in the maize nested association mapping population. Nat Genet 43:163–169CrossRefGoogle Scholar
  26. Mafu S, Ding Y, Murphy KM et al (2018) Discovery, biosynthesis and stress-related accumulation of dolabradiene-derived defenses in maize. Plant Physiol 176:2677–2690CrossRefGoogle Scholar
  27. McMullen M, Simcox KD (1995) Genomic organization of disease and insect resistance genes in maize. Mol Plant-Microbe Interact 8:811–815CrossRefGoogle Scholar
  28. Meeley RB, Walton JD (1991) Enzymatic detoxification of HC-toxin, the host-selective cyclic peptide from Cochliobolus carbonum. Plant Physiol 97:1080–1086CrossRefGoogle Scholar
  29. Meyer J, Berger DK, Christensen SA, Murray SL (2017) RNA-Seq analysis of resistant and susceptible sub-tropical maize lines reveals a role for kauralexins in resistance to grey leaf spot disease, caused by Cercospora zeina. BMC Plant Biol 17:1–20CrossRefGoogle Scholar
  30. Moscou MJ, Lauter N, Steffenson B, Wise RP (2011) Quantitative and qualitative stem rust resistance factors in barley are associated with transcriptional suppression of defense regulons. PLoS Genet 7(7):e1002208CrossRefGoogle Scholar
  31. Mueller DS, Wise KA, Sisson AJ et al (2016) Corn yield loss estimates due to diseases in the United States and Ontario, Canada from 2012 to 2015. Plant Heal Prog 17:211–222CrossRefGoogle Scholar
  32. Meuwissen TH, Hayes BJ, Goddard ME (2001) Prediction of total genetic value using genome-wide dense marker maps. Genetics 157(4):1819–1829PubMedPubMedCentralGoogle Scholar
  33. Mundt CC (2014) Durable resistance: a key to sustainable management of pathogens and pests. Infect Genet Evol 27:446–455CrossRefGoogle Scholar
  34. Munkvold GP, White DG (2016) Compendium of corn diseases, 4th edn. APS Press, The American Phytopathological Society, St. PaulGoogle Scholar
  35. Nelson R, Wiesner-Hanks T, Wisser R, Balint-Kurti P (2018) Navigating complexity to breed disease-resistant crops. Nat Rev Genet 19:21–33CrossRefGoogle Scholar
  36. Oerke E-C, Dehne H-W, Schönbeck F et al (1999) Estimated crop losses due to pathogens, animal pests and weeds. Crop production and crop protection. Elsevier, New York, pp 72–741CrossRefGoogle Scholar
  37. Panaccione DG, Scott-Craig JS, Pocard JA, Walton JD (1992) A cyclic peptide synthetase gene required for pathogenicity of the fungus Cochliobolus carbonum on maize. Proc Natl Acad Sci USA 89:6590–6594CrossRefGoogle Scholar
  38. Poland JA, Balint-Kurti PJ, Wisser RJ et al (2009) Shades of gray: the world of quantitative disease resistance. Trends Plant Sci 14:21–29CrossRefGoogle Scholar
  39. Poland JA, Bradbury PJ, Buckler ES, Nelson RJ (2011) Genome-wide nested association mapping of quantitative resistance to northern leaf blight in maize. Proc Natl Acad Sci USA 108:6893–8CrossRefGoogle Scholar
  40. Poland J, Rutkoski J (2016) Advances and challenges in genomic selection for disease resistance. Annu Rev Phytopathol 54:79–98CrossRefGoogle Scholar
  41. Scheffer RP, Nelson RR, Ullstrup AJ (1967) Inheritance of toxin production and pathogenicity in Cochliobolus carbonum and Cochliobolus victoriae. Phytopathology 57:1288Google Scholar
  42. Schmelz EA, Huffaker A, Sims JW et al (2014) Biosynthesis, elicitation and roles of monocot terpenoid phytoalexins. Plant J 79:659–678CrossRefGoogle Scholar
  43. Schmelz EA, Kaplan F, Huffaker A et al (2011) Identity, regulation, and activity of inducible diterpenoid phytoalexins in maize. Proc Natl Acad Sci 108:5455–5460CrossRefGoogle Scholar
  44. Schnable PS, Ware D, Fulton RS et al (2009) The B73 maize genome: complexity, diversity, and dynamics. Science 326:1112–1115CrossRefGoogle Scholar
  45. Scott-Craig JS, Panaccione DG, Pocard JA, Walton JD (1992) The cyclic peptide synthetase catalyzing HC-toxin production in the filamentous fungus Cochliobolus carbonum is encoded by a 15.7-kilobase open reading frame. J Biol Chem 267:26044–26049PubMedGoogle Scholar
  46. St Clair DA (2010) Quantitative disease resistance and quantitative resistance Loci in breeding. Annu Rev Phytopathol 48:247–68CrossRefGoogle Scholar
  47. Tatum LA (1971) The southern corn leaf blight epidemic. Science 171:1113–1116CrossRefGoogle Scholar
  48. Technow F, Bürger A, Melchinger AE (2013) Genomic prediction of northern corn leaf blight resistance in maize with combined or separated training sets for heterotic groups. G3 Genes Genomes Genet 3:197–203Google Scholar
  49. Tsuda K, Somssich IE (2015) Transcriptional networks in plant immunity. New Phytol 206:932–947CrossRefGoogle Scholar
  50. Ullstrup AJ (1972) The impacts of the southern corn leaf blight epidemics of 1970–1971. Annu Rev Phytopathol 10:37–50CrossRefGoogle Scholar
  51. Van Der Plank JE (1963) Plant diseases: epidemics and control. Academic Press, New YorkGoogle Scholar
  52. Van Der Plank JE (1966) Horizontal (polygenic) and vertical (oligogenic) resistance against blight. Am Potato J 43:43–52CrossRefGoogle Scholar
  53. Wallace JG, Bradbury PJ, Zhang N et al (2014) Association mapping across numerous traits reveals patterns of functional variation in maize. PLoS Genet 10(12):e1004845CrossRefGoogle Scholar
  54. Walley JW, Shen Z, McReynolds MR et al (2018) Fungal-induced protein hyperacetylation in maize identified by acetylome profiling. Proc Natl Acad Sci 115:210–215CrossRefGoogle Scholar
  55. Walton JD, Akimitsu K, Ahn JH, Pitkin JW (1994) Towards an understanding of the TOX2 gene of Cochliobolus carbonum. In: Kohmoto K, Yoder OC (eds.) Proceedings of the second Tottori University international symposium on host-specific toxin: biosynthesis, receptor and molecular biology, pp 227–237Google Scholar
  56. Walton JD, Earle ED, Gibson BW (1982) Purification and structure of the host-specific toxin from Helminthosporium carbonum race 1. Biochem Biophys Res Commun 107:785–794CrossRefGoogle Scholar
  57. Wisser RJ, Balint-Kurti PJ, Nelson RJ (2006) The genetic architecture of disease resistance in maize: a synthesis of published studies. Phytopathology 96:120–129CrossRefGoogle Scholar
  58. Yan Y, Christensen S, Isakeit T et al (2012) Disruption of OPR7 and OPR8 reveals the versatile functions of jasmonic acid in maize development and defense. Plant Cell 24:1420–1436CrossRefGoogle Scholar
  59. Yang Q, Balint-Kurti P, Xu M (2017) Quantitative disease resistance: dissection and adoption in maize. Mol Plant 10:402–413CrossRefGoogle Scholar
  60. Yu X, Li X, Guo T et al (2016) Genomic prediction contributing to a promising global strategy to turbocharge gene banks. Nat Plants 2:1–7Google Scholar

Copyright information

© Springer Nature Switzerland AG 2018

Authors and Affiliations

  1. 1.Department of Plant and Soil SciencesUniversity of DelawareNewarkUSA
  2. 2.Corn Insects and Crop Genetics Research UnitUSDA-ARSAmesUSA
  3. 3.Department of Plant Pathology and MicrobiologyIowa State UniversityAmesUSA

Personalised recommendations