EUS-Guided Therapies for Solid Pancreatic Tumors Including Drug Delivery and Brachytherapy

  • Gursimran Singh Kochhar
  • Michael WallaceEmail author


Endoscopic ultrasound (EUS) has dramatically changed in last five decades of its use in the management of gastrointestinal diseases. EUS has evolved from its original intent, to image the pancreas, to enable fine-needle tissue sampling and drug delivery. With the improvement in technology, the indications for EUS will continue to expand. In this chapter, we will discuss some of the recent advances made in the field of therapeutic EUS and its use in management of solid pancreatic tumors.


Endoscopic ultrasound Pancreas Solid lesions Radio frequency ablation Solid pancreatic tumors Fine-needle aspiration Brachytherapy Fiducial placement 



Computed tomography


Dendritic cells


Endoscopic ultrasound


Fine-needle aspiration


Fine-needle injection


Hepatocellular carcinoma


Photodynamic therapy


Pancreatic neuroendocrine tumor


Radio frequency ablation



Supplementary material

Video 11.1

EUS-guided radiofrequency ablation of a pancreatic neuroendocrine tumor . (Reprinted from VideoGIE, Radiofrequency ablation devices, 2(10), Navaneethan U et al., October 1, 2017, with permission from Elsevier) (MP4 10172 kb)


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of Gastroenterology and HepatologyThe Mayo ClinicJacksonvilleUSA

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