Influence of Elevated Temperature During Crimping on Results of Numerical Simulation of a Bioresorbable Stent Deployment Process
Bioresorbable stents (BRSs) represent a promising technological development within the field of cardiovascular angioplasty because of their ability to avoid long-term side effects of conventional stents such as in-stent restenosis, late stent thrombosis and fatigue induced strut fracture. However polymer materials used for production of some of the BRSs pose new challenges raising from the fact, that mechanical properties of polymers are very different from the metallic materials used to make stents before BRSs era. These challenges manifests not only in clinical practice but mainly in the process of design of the new device. This especially applies to Finite Element based numerical simulations of the stent structure, as the first-choice tool to examine newly developed stent in early stage of design process. In the article authors investigating different scenarios of numerical simulation of stent deployment process. The goal of the exercise is to find a proper way to model influence of elevated temperature present during crimping on the behaviour of the stent.
KeywordsBioresorbable stent Finite element analysis Biodegradable material mechanics
The study was supported by the NCBiR within project “Apollo” (STRATEGMED) and the Interdisciplinary Centre for Mathematical and Computational Modelling (ICM) of the University of Warsaw under grant no. GB65-19. This support is gratefully acknowledged.
- 1.Barton, M., Grüntzig, J., Husmann, M., Rösch, J.: Balloon angioplasty – the legacy of andreas grüntzig, M.D. (1939–1985). Front. Cardiovasc. Med. 1, 15 (2014)Google Scholar
- 3.Moses, J.W., Leon, M.B., Popma, J.J., Fitzgerald, P.J., Holmes, D.R., O’Shaughnessy, C., Caputo, R.P., Kereiakes, D.J., Williams, D.O., Teirstein, P.S., Jaeger, J.L.: Sirolimus-eluting stents versus standard stents inpatients with stenosis in a native coronary artery. New Engl. J. Med. 349(14), 1315–1323 (2003)CrossRefGoogle Scholar
- 4.Stone, W.G., Ellis, G.S., Cox, A.D., Hermiller, J., O’Shaughnessy, C., Mann, T.J., Turco, M., Caputo, R., Bergin, P., Greenberg, J., Popma, J.J., Rusell, E.M.: A polymer-based, paclitaxel-eluting stent in patients with coronary artery disease. N. Engl. J. Med. 350(3), 221–231 (2004)CrossRefGoogle Scholar
- 6.Grech, E.D.: ABC of Interventional Cardiology, 2nd edn. Wiley-Blackwell, West Sussex (2011)Google Scholar
- 8.Onuma, Y., Serruys, W.P.: Bioresorbable scaffold the advent of a new era in percutaneous coronary and peripheral revascularization? New Drugs Technol. Circ. 123(7), 779–797 (2011)Google Scholar
- 12.Bukala, J., Malachowski, J., Kwiatkowski, P.: Finite element analysis of the percutaneous coronary intervention in a coronary bifurcation. Acta Bioeng. Biomech. 16(4), 23–31 (2014)Google Scholar