Impedimetric Method to Monitor Biological Layer Formation on Central Venous Catheters for Hemodialysis Made of Carbothane

  • Ewa ParadowskaEmail author
  • Marta Nycz
  • Katarzyna Arkusz
  • Bartosz Kudliński
  • Elżbieta Krasicka-Cydzik
Conference paper
Part of the Advances in Intelligent Systems and Computing book series (AISC, volume 831)


The aim of the study was to specify by an impedimetric method the changes observed on the inner wall of central venous catheters for hemodialysis leading to the formation of a biological film. To evaluate these changes a patient-dialyzer model was built in which experimental parameters were kept closely similar to the clinical conditions of hemodialysis. The impedance spectra and SEM/EDS analysis of the biological layer deposited on the inner surface of the distal part of the catheter gave an insight into the structure of film formation and its chemical composition. Since an early detection of biofilm formation inside the distal part of the catheter is crucial for the safety of medical treatment and it usually prompts the implementation of antibiotic therapy. Developed impedimetric method can minimize the risk of infection and ensure the continuity of treatment.


Central venous catheters Electrochemical impedance spectroscopy Biological layer Scanning electron microscopy 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Ewa Paradowska
    • 1
    Email author
  • Marta Nycz
    • 1
  • Katarzyna Arkusz
    • 1
  • Bartosz Kudliński
    • 2
  • Elżbieta Krasicka-Cydzik
    • 1
  1. 1.Biomedical Engineering DivisionUniversity of Zielona GoraZielona GoraPoland
  2. 2.Department of Intensive CareZielona Gora University HospitalZielona GoraPoland

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