Massive Perivillous Fibrinoid Deposition and Maternal Floor Infarct

  • Philip J. Katzman
  • Linda M. Ernst
  • Irene B. Scheimberg


Massive perivillous fibrinoid deposition (MPVFD) and maternal floor infarct (MFI) are part of a spectrum of lesion in which fibrinoid material is laid down between chorionic villi. These lesions can be recurrent and are associated with fetal growth restriction and, when severe, intrauterine fetal demise.


Chorionic villus Fetal growth restriction Fibrin Infarction Recurrence Thrombus 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Philip J. Katzman
    • 1
  • Linda M. Ernst
    • 2
    • 3
  • Irene B. Scheimberg
    • 4
    • 5
  1. 1.Department of Pathology and Laboratory MedicineUniversity of Rochester Medical CenterRochesterUSA
  2. 2.NorthShore University Healthsystem, Evanston HospitalEvanstonUSA
  3. 3.The University of Chicago Pritzker School of MedicineChicagoUSA
  4. 4.Queen Mary University College Medical SchoolLondonUK
  5. 5.Department of Cellular PathologyThe Royal London Hospital, Barts Health NHS TrustLondonUK

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