Acute Inflammation

  • Phillip CoxEmail author
  • Marta C. Cohen
  • Irene B. Scheimberg


Acute chorioamnionitis comprises acute inflammation of the chorionic plate of the placenta, the amniochorial membrane and the umbilical cord. Most cases are the result of acute bacterial infection of the amniotic fluid/amniotic cavity, with the potential to spread to the fetus to initiate preterm labour or to cause maternal sepsis.

In the amniochorial membrane, the inflammatory response is of maternal origin. By histological examination the inflammatory response can show a range of extent and severity, which should be recorded in the histology report, either descriptively or as a grade and stage.


Amniochorial membranes Acute chorioamnionitis Inflammation Infection Maternal inflammatory response Placenta 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Phillip Cox
    • 1
    Email author
  • Marta C. Cohen
    • 2
  • Irene B. Scheimberg
    • 3
    • 4
  1. 1.Birmingham Women’s and Children’s NHS TrustBirminghamUK
  2. 2.Sheffield Children’s Hospital NHS FTSheffieldUK
  3. 3.Queen Mary University College Medical SchoolLondonUK
  4. 4.Department of Cellular PathologyThe Royal London Hospital, Barts Health NHS TrustLondonUK

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