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Laminar Necrosis, Membrane Chorionic Microcysts and Chorion Nodosum

  • Jerzy StanekEmail author
Chapter

Abstract

Three grossly inapparent lesions, membrane laminar necrosis (LN), membrane chorionic microcysts (MCM) and chorion nodosum (ChN), may be microscopically seen in placental membranes. LN is a relatively common and nonspecific acute hypoxic membrane lesion (membrane infarction) that may be seen in in utero hypoxia of various origins. It features laminar coagulative necrosis of the decidual layer, trophoblastic layer or both at the choriodecidual interphase of placental membranes. MCM is a chronic hypoxic membrane placental lesion associated with shallow placental implantation and increased amount of extravillous trophoblastic cells in placental membranes and chorionic disc. It features small pseudocysts, frequently confluent, in the invasive trophoblastic layer. MCM are typically seen in preeclampsia, maternal diabetes mellitus and fetal growth restriction. ChN is a placental lesion formed in the chorionic mesenchyme of membranes denuded of amnion in the extraamniotic pregnancy and the limb-body wall complex.

Keywords

Placenta Laminar necrosis Chorionic microcysts Chorion nodosum Shallow placental implantation In utero hypoxia 

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Division of PathologyCincinnati Children’s Hospital Medical CenterCincinnatiUSA

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