Advertisement

Miscellaneous Lesions of the Villous Parenchyma

  • M. Halit PinarEmail author
  • Salwa Khedr
Chapter

Abstract

In this chapter, some rare and some more common findings are discussed. Calcification in the placenta is a frequent finding. Although frequently it does not have any known clinical consequences, it is a sign of significant pathology in some cases. Presence of heterotopic tissue in the placental parenchyma is rare, but these interesting lesions underline our limited knowledge of the development of the placenta.

Keywords

Calcification Heterotopia Fibrinoid necrosis 

References

  1. 1.
    Mastrolia SA, Weintraub AY, Sciaky-Tamir Y, Tirosh D, Loverro G, Hershkovitz R. Placental calcifications: a clue for the identification of high-risk fetuses in the low-risk pregnant population? J Matern Neonatal Med. 2016;29:921–7.CrossRefGoogle Scholar
  2. 2.
    Jamal A, Moshfeghi M, Moshfeghi S, Mohammadi N, Zarean E, Jahangiri N. Is preterm placental calcification related to adverse maternal and foetal outcome? J Obstet Gynaecol (Lahore). 2017;37:605–9.CrossRefGoogle Scholar
  3. 3.
    Avery CR, Aterman K. Calcification of the basement-membrane of placental villi. J Pathol. 1971;103:199–200.CrossRefGoogle Scholar
  4. 4.
    Chia C-C, Huang S-C. Recurrent placental microcalcifications in the second trimester. Taiwan J Obstet Gynecol. 2010;49:357–8.CrossRefGoogle Scholar
  5. 5.
    Husain SM, Mughal MZ. Mineral transport across the placenta. Arch Dis Child. 1992;67:874–8.CrossRefGoogle Scholar
  6. 6.
    Varma VA, Kim KM. Placental calcification: ultrastructural and X-ray microanalytic studies. Scan Electron Microsc. 1985;(Pt 4):1567–72.Google Scholar
  7. 7.
    Zeng J, Marcus A, Buhtoiarova T, Mittal K. Distribution and potential significance of intravillous and intrafibrinous particulate microcalcification. Placenta. 2017;50:94–8.CrossRefGoogle Scholar
  8. 8.
    Sherer D, Allen T, Metlay L, Abramowitz J. Linear calcification in a placental infarct causing complete distal sonographic shadowing. J Clin Ultrasound. 1994;22:212–3.CrossRefGoogle Scholar
  9. 9.
    Benirschke K, Pekarske S. Placental pathology casebook: extensive calcification of the umbilical cord and placenta. J Perinatol. 1995;15:81–3.PubMedGoogle Scholar
  10. 10.
    Harris RD, Cho C, Wells WA. Sonography of the placenta with emphasis on pathological correlation. Semin Ultrasound CT MR. 1996;17:66–89.CrossRefGoogle Scholar
  11. 11.
    Brown HL, Miller JM Jr, Khawli O, Gabert HA. Premature placental calcification in maternal cigarette smokers. Obstet Gynecol. 1988;71:914–7.PubMedGoogle Scholar
  12. 12.
    Klesges LM, Murray DM, Brown JE, Cliver SP, Goldenberg RL. Relations of cigarette smoking and dietary antioxidants with placental calcification. Am J Epidemiol. 1998;147:127–35.CrossRefGoogle Scholar
  13. 13.
    Hofmeyr GJ, Moolla S, Lawrie T. Prenatal sonographic diagnosis of congenital varicella infection—a case report. Prenat Diagn. 1996;16:1148–51.CrossRefGoogle Scholar
  14. 14.
    Lu H, Guo YN, Liu SN, Zhu H, Zhang DC. Isolation, cultivation and identification of nanobacteria from placental calcification. J Matern Fetal Neonatal Med. 2012;25:2182–5.CrossRefGoogle Scholar
  15. 15.
    Ernst LM, Parkash V. Placental pathology in fetal Bartter syndrome. Pediatr Dev Pathol. 2002;5:76–9.CrossRefGoogle Scholar
  16. 16.
    Tan WC, Rodeck CH. Placental calcification in pseudoxanthoma elasticum. Ann Acad Med Singap. 2007;7:598–600.Google Scholar
  17. 17.
    Shimada T, Inoue T, Abe S, Hiraki K, Miura K, Hayashi T, et al. Placental multiple chorionic cysts in maternal scleroderma. J Med Ultrasound. 2010;37:209–12.CrossRefGoogle Scholar
  18. 18.
    Guschmann M, Vogel M, Urban M. Adrenal tissue in the placenta: a heterotopia caused by migration and embolism? Placenta. 2000;21:427–31.CrossRefGoogle Scholar
  19. 19.
    Labarrere CA, Caccamo D, Telenta M, Althabe O, Gutman R. A nodule of adrenocortical tissue within a human placenta: light microscopic and immunocytochemical findings. Placenta. 1984;5:139–43.CrossRefGoogle Scholar
  20. 20.
    Qureshi F, Jacques SM. Adrenocortical and hepatic nodules within placental tissue. Pediatr Pathol Lab Med. 2003;5:464–6.Google Scholar
  21. 21.
    Vesoulis Z, Agamanolis D. Benign hepatocellular tumor of the placenta. Am J Surg Pathol. 1998;22:355–9.CrossRefGoogle Scholar
  22. 22.
    Khedr S, Jazaerly T, Kostadinov S. Placental teratoma, omphalomesenteric duct remnant or intestinal organoid (enteroid) differentiation: a diagnostic dilemma. J Pediatr Genet. 2017;22:355–9.Google Scholar
  23. 23.
    Chen KT, Ma CK, Kassel SH. Hepatocellular adenoma of the placenta. Am J Surg Pathol. 1986;10:436–40.CrossRefGoogle Scholar
  24. 24.
    Khalifa MA, Gersell DJ, Hansen CH, Lage JM. Hepatic (hepatocellular) adenoma of the placenta: a study of four cases. Int J Gynecol Pathol. 1998;17:241–4.CrossRefGoogle Scholar
  25. 25.
    Fox H. Fibrinoid necrosis of placental villi. Br J Obstet Gynaecol. 1968;75:448–52.CrossRefGoogle Scholar
  26. 26.
    Shams F, Rafique M, Samoo NA, Irfan R. Fibrinoid necrosis and hyalinization observed in normal, diabetic and hypertensive placentae. J Coll Physicians Surg Pak. 2012;22:769–72.PubMedGoogle Scholar
  27. 27.
    Liebhart M. Some observations on so-called fibrinoid necrosis of placental villi. An electron-microscopic study. Pathol Eur. 1971;6:217–26.PubMedGoogle Scholar
  28. 28.
    McCormick JN, Faulk WP, Fox H, Fudenberg HH. Immunohistological and elution studies of the human placenta. J Exp Med. 1971;133:1–18.CrossRefGoogle Scholar
  29. 29.
    Burstein R, Frankel S, Soule SD, Blumenthal HT. Aging of the placenta: autoimmune theory of senescence. Am J Obstet Gynecol. 1973;116:271–6.CrossRefGoogle Scholar
  30. 30.
    Evers IM, Nikkels PG, Sikkema JM, Visser GH. Placental pathology in women witht type 1 diabetes and in a control group with normal and large for gestational age infants. Placenta. 2003;24:619–25.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Division of Perinatal and Pediatric Pathology, Department of Pathology and Laboratory MedicineWomen and Infants Hospital of Rhode Island and Alpert School of Medicine at Brown UniversityProvidenceUSA

Personalised recommendations