Introduction: An Approach to Placental Pathology

  • T. Yee KhongEmail author
  • Eoghan E. Mooney
  • Sanne J. Gordijn
  • Terry K. Morgan
  • Peter G. J. Nikkels


The reasons and diagnostic challenges of a pathological examination of the placenta are discussed briefly. This chapter outlines a topographical approach to such an examination. The clinical relevance of placental examination is discussed also. Suggestions are presented of how more robust evidence of clinical significance can be obtained. Interactions between placental pathology, basic science research and clinical correlation will enhance the value of placental pathology.


Gross examination Macroscopic findings Histopathology Mother Neonate Fetus Basic science Clinical correlation Evidence Report 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • T. Yee Khong
    • 1
    • 2
    Email author
  • Eoghan E. Mooney
    • 3
  • Sanne J. Gordijn
    • 4
  • Terry K. Morgan
    • 5
  • Peter G. J. Nikkels
    • 6
  1. 1.SA PathologyWomen’s and Children’s HospitalNorth AdelaideAustralia
  2. 2.University of AdelaideAdelaideAustralia
  3. 3.Department of Pathology and Laboratory MedicineNational Maternity HospitalDublinIreland
  4. 4.Department of Obstetrics and Gynaecology, University Medical Center GroningenUniversity of GroningenGroningenThe Netherlands
  5. 5.Department of PathologyOregon Health and Science UniversityPortlandUSA
  6. 6.Department of PathologyUniversity Medical Center UtrechtUtrechtThe Netherlands

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