Plant Proteolytic Enzymes: Their Role as Natural Pharmacophores

  • Carlos E. SalasEmail author
  • Dalton Dittz
  • Maria-Jose Torres


Proteases or proteinases are enzymes that catalyze cleavage of proteins at peptide bonds generating smaller peptides. Some of them are very specific in their choice of target site while others act rather nonspecifically and hydrolyze the protein substrate if conditions allow into short peptides. They must have appeared early in evolution along with proteins, to keep a balance between synthesis and protein degradation. Their early emergence is confirmed by their ubiquitous presence in most living forms including viruses, plants, and animals.


Inflammation Immunomodulation Wound healing Antitumoral Dalton Bioactive peptides Protease inhibitors 


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Copyright information

© Springer Nature Switzerland AG 2018

Authors and Affiliations

  • Carlos E. Salas
    • 1
    Email author
  • Dalton Dittz
    • 1
  • Maria-Jose Torres
    • 2
  1. 1.Instituto de Ciências Biológicas, Departamento de Bioquímica e ImunologiaUniversidade Federal de Minas FeraisBelo HorizonteBrazil
  2. 2.Departamento de Ingeniería de AlimentosUniversidad de la SerenaLa SerenaChile

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