Endoscopic Management of Benign Submucosal Tumors

  • Ran Bill LuoEmail author
  • Garth R. Jacobsen


Benign submucosal tumors in the upper gastrointestinal (GI) tract are typically discovered incidentally either on routine or surveillance upper endoscopies. Common pathologies include leiomyomas, lipomas, carcinoids, cysts, and ectopic pancreas tissue. Endoscopic ultrasound (EUS) should be performed preoperatively to assess the depth of penetration prior to consideration for endoscopic intervention. The two most common techniques for endoscopic excision of benign lesions are endoscopic mucosal resection (EMR), which is used for masses smaller than 2 cm, and endoscopic submucosal dissection (ESD), which is used for masses larger than 2 cm. Two alternative techniques of unroofing and enucleation are less commonly employed but appear effective.


Endoscopic resection Submucosal Benign Foregut Gastric Esophageal 


  1. 1.
    Shim CS, Jung IS. Endoscopic removal of submucosal tumors: preprocedure diagnosis, technical options, and results. Endoscopy. 2005;37(7):646–54.CrossRefGoogle Scholar
  2. 2.
    Fukuda S, Yamagata R, Mikami T, et al. Gastric lipoma successfully treated by endoscopic unroofing. Dig Endosc. 2003;15:228–31.CrossRefGoogle Scholar
  3. 3.
    Kopáčová M, Rejchrt S, Bureš J. Unroofing technique as an option for the endoscopic treatment of giant gastrointestinal lipomas. Acta Med (Hradec Kralove). 2015;58(4):115–8.CrossRefGoogle Scholar
  4. 4.
    Park YS, Park SW, Kim TI, et al. Endoscopic enucleation of upper GI submucosal tumors by using an insulated−tip electrosurgical knife. Gastrointest Endosc. 2004;59(3):409–15.CrossRefGoogle Scholar
  5. 5.
    Lee KJ, Kim GH, Park DY, et al. Endoscopic resection of gastrointestinal lipomas: a single-center experience. Surg Endosc. 2014;28(1):185–92.CrossRefGoogle Scholar

Copyright information

© SAGES 2019

Authors and Affiliations

  1. 1.Division of Minimally Invasive Surgery, Department of General SurgeryUC San Diego Health SystemsLa JollaUSA
  2. 2.Department of SurgeryUniversity of California San DiegoRancho Santa FeUSA

Personalised recommendations