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Expert Commentary: Surveillance Versus Ablation for Patients with Low-Grade Dysplasia

  • John G. Hunter
  • Joseph M. DrosdeckEmail author
Chapter

Abstract

The diagnosis and management of low-grade dysplasia (LGD) in the setting of Barrett’s esophagus continues to challenge physicians. Interobserver variability among pathologists remains high, and clinicians lack accurate models to predict those at risk of progressing to high-grade dysplasia and esophageal adenocarcinoma. Radiofrequency ablation (RFA) offers a safe and effective treatment option for LGD with acceptable risks, given the unpredictable natural course of the disease. Although current evidence suggests that RFA is cost-effective, long-term data is not yet available. However, patients experience an improvement in disease-specific health-related quality of life. Therefore, RFA should be considered in all patients with LGD.

Keywords

Barrett’s esophagus Intestinal metaplasia Low-grade dysplasia Endoscopic ablation Radiofrequency ablation 

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Copyright information

© SAGES 2019

Authors and Affiliations

  1. 1.Department of SurgeryOHSUPortlandUSA
  2. 2.Department of General SurgeryThe Everett ClinicEverettUSA

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