Clinical Concepts of Brain Tumors

  • Carlotta Chiavazza
  • Federica Franchino
  • Roberta Rudà


Neurological symptoms and signs of brain tumors are not specifically tied to individual specific tumor types, but rather to location within the central nervous system (CNS). Tumor can damage neural tissue by infiltration or displace by compression, leading to focal symptoms. Direct invasion from a tumor typically occurs in gliomas, whereas meningiomas displace normal brain. The disruption of the blood–brain barrier by the tumor leads to vasogenic edema that is one of the main causes of neurological impairment: edema favors an increase of mass effect and thus a further compression of the surrounding brain [1].


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Carlotta Chiavazza
    • 1
  • Federica Franchino
    • 1
  • Roberta Rudà
    • 1
  1. 1.Department of Neuro-OncologyUniversity and City of Health and Science HospitalTurinItaly

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