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Clinical Trials on Aging Research

  • Mario Ulises Pérez-ZepedaEmail author
  • Antonio Cherubini
  • Carmen García-Peña
  • Elisa Zengarini
  • Luis Miguel Gutiérrez-Robledo
Chapter

Abstract

Clinical trials are considered to be one of the best methodologies in health research and they are used primarily to test interventions in medicine. Aging research is no exception for this goal, and clinical trials are used to test different interventions in older adults with a number of variations in this particular research. In addition to drugs, in older adult’s diverse non-pharmacological interventions are experimented for a wide-array of diseases and conditions that are particular for this age group. A careful design and sometimes adaptation of clinical trials methodology are necessary to have accurate results and translate them into actions in everyday clinical care of the older adult. Below, we provide a general and schematic review of the theoretical concept of clinical trials and their variants, followed by examples of interventions and specific outcomes in research on older adults.

Keywords

Clinical trials Pragmatic trials Interventions for older adults 

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Mario Ulises Pérez-Zepeda
    • 1
    Email author
  • Antonio Cherubini
    • 2
  • Carmen García-Peña
    • 3
  • Elisa Zengarini
    • 2
  • Luis Miguel Gutiérrez-Robledo
    • 4
  1. 1.Department of Geriatric EpidemiologyNational Institute of GeriatricsMexico CityMexico
  2. 2.Geriatria, Accettazione geriatrica e Centro di ricerca per l’invecchiamento. IRCCS-INRCAAnconaItaly
  3. 3.Research DivisionNational Institute of GeriatricsMexico CityMexico
  4. 4.National Institute of GeriatricsMexico CityMexico

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