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Overview of Cell Signaling Pathways in Cancer

  • Amanda J. Harvey
Chapter

Abstract

There are many different signaling pathways that contribute to development and cellular homeostasis. In diseases, especially cancer, development components of these pathways often become mutated or overexpressed causing dysregulation of cellular signaling. This chapter provides an overview of the key pathways involved in tumor development and progression and studies some of the complications associated with therapeutic targeting, namely, signaling cross talk and biomarker identification.

Keywords

EGFR Cancer Cell signaling Biomarkers Therapeutic targets MAPK 

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of Life SciencesBrunel University LondonUxbridgeUK

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