Advertisement

Clinical Features, Case Definition and Clinical Management of Ebola Virus Disease

  • Marta LadoEmail author
  • Colin S. Brown
  • Naomi F. Walker
  • Daniel Youkee
  • Oliver Johnson
  • Andy Hall
  • Patrick Howlett
  • Hooi-Ling Harrison
  • Felicity Fitzgerald
  • Natalie Mounter
Chapter

Abstract

The Ebola virus and the Marburg virus together form the family of Filoviridae. The Filoviruses are thread-like RNA viruses that cause fever and haemorrhagic complications. The Filoviruses cause severe disease in humans and non-human primates (gorillas, chimpanzees and monkeys) with an extremely high case fatality rate in humans ranging from 25 to 90% depending on the subtype and the availability of medical care.

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Marta Lado
    • 1
    • 2
    Email author
  • Colin S. Brown
    • 3
    • 4
    • 10
  • Naomi F. Walker
    • 5
    • 6
  • Daniel Youkee
    • 3
  • Oliver Johnson
    • 3
  • Andy Hall
    • 3
  • Patrick Howlett
    • 2
  • Hooi-Ling Harrison
    • 7
  • Felicity Fitzgerald
    • 8
  • Natalie Mounter
    • 9
  1. 1.King’s Sierra Leone PartnershipFreetownSierra Leone
  2. 2.King’s Sierra Leone Partnership, King’s Centre for Global Health, King’s College London and King’s Health PartnersFreetownSierra Leone
  3. 3.King’s Sierra Leone Partnership, King’s Centre for Global Health, King’s Health PartnersKing’s College LondonLondonUK
  4. 4.Department of InfectionRoyal Free London NHS Foundation TrustLondonUK
  5. 5.Department of Clinical ResearchLondon School of Hygiene and Tropical MedicineLondonUK
  6. 6.Hospital for Tropical DiseasesUniversity College London HospitalLondonUK
  7. 7.King’s Sierra Leone Partnership, King’s Centre for Global Health, Weston Education CentreLondonUK
  8. 8.Infection, Immunity, Inflammation and Physiological Medicine, UCL Great Ormond Street Institute of Child HealthLondonUK
  9. 9.Solent NHS TrustSouthamptonUK
  10. 10.National Infection ServicePublic Health EnglandLondonUK

Personalised recommendations