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Cardiopulmonary Interactions in Adults with Congenital Heart Disease

  • Ronald A. BronickiEmail author
  • Andrew N. Redington
Chapter
Part of the Congenital Heart Disease in Adolescents and Adults book series (CHDAA)

Abstract

The population of adults with congenital heart disease (CHD) has increased dramatically over the past few decades, with the number of adults with CHD now surpassing the pediatric population. Adult CHD (ACHD) encompasses a broad range of presentations, with some patients diagnosed for the first time in adulthood. The majority of patients however have undergone a palliative repair during childhood and now are dealing with sequela and/or residual disease years to decades later. All of which may be compounded by acquired cardiovascular disease. In this review, we describe the physiologic underpinnings of the interaction between the respiratory and cardiovascular systems and their clinical impact in ACHD. We will review the physiologic underpinnings of cardiopulmonary interactions and the effects of respiration on cardiovascular function, the impact of respiration on cardiovascular function in adult patients with congenital and acquired heart disease, the effects of respiratory disease on cardiovascular function, and the impact of cardiovascular disease on respiratory function.

Keywords

Adult congenital heart disease Cardiopulmonary interactions Compliance Transmural pressure Systemic venous return Ventricular preload Ventricular afterload Ventricular interaction Cardiac output Systemic oxygen delivery 

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Sections of Critical Care Medicine and CardiologyBaylor College of Medicine, Texas Children’s HospitalHoustonUSA
  2. 2.Cincinnati College of Medicine, Cincinnati Children’s Hospital Medical CenterCincinnatiUSA

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