Medical Work-Up of the Deceased Donor

  • Anne C. Davis
  • Rebecca Flyckt
  • Tommaso FalconeEmail author


This chapter overviews the history of deceased donor uterus transplantation and explores the major components of the medical evaluation of a deceased uterine donor. That includes obtaining the medical and surgical history, serological and microbiological evaluation, and preoperative imaging. Moreover, the challenges associated with obtaining consent from a deceased donor’s family will be discussed.


  1. Del Priore G, Stega J, Sieunarine K, et al. Human uterus retrieval from a multi-organ donor. Obstet Gynecol. 2007;109:101–4.CrossRefGoogle Scholar
  2. Erman A, Ozkan O, Aydinuraz B, Dirican K, Cincik M, Mendilcioglu I, et al. Clinical pregnancy after uterus transplantation. Fertil Steril. 2013;100:1358–63.CrossRefGoogle Scholar
  3. Flyckt R, Falcone T, Eghtesad B, Fung J, Tzakis A. Uterus transplantation: medical considerations. Curr Transplant Rep. 2016;3:380–4.CrossRefGoogle Scholar
  4. Flyckt R, Kotylar A, Arian S, Eghtesad B, Falcone T, Tzakis A. Deceased donor uterine transplantation. Fertil Steril. 2017;107:e13.CrossRefGoogle Scholar
  5. Flyckt R, Davis A, Farrell R, Zimberg S, Tzakis A, Falcone T. Uterine transplantation: surgical innovation in the treatment of uterine factor infertility. J Obstet Gynaecol Can. 2018;40(1):86–93.CrossRefGoogle Scholar
  6. Fronek J, Janousek L, Chmel R. Deceased donor uterus retrieval—the first Czech experience. Rozhl Chir. 2016;95:312–6.PubMedGoogle Scholar
  7. Gautheir T, Piver P, Pichon N, et al. Uterus retrieval process from brain dead donors. Fertil Steril. 2014;102:476–82.CrossRefGoogle Scholar
  8. Jones B, Saso S, Yazbek J, Smith J. Uterine transplantation: past, present and future. BJOG. 2016;123:1434–8.CrossRefGoogle Scholar
  9. Ozkan O, Akar ME, Erdogan O, Ozkan O, Hadimioglu N. Uterus transplantation from a deceased donor. Fertil Steril. 2013;100:e41.CrossRefGoogle Scholar
  10. Rodrigue J, Tomich D, Fleishman A, Glazier A. Vascularized composite allograft donation and transplantation: a survey of public attitudes in the United States. Am J Transplant. 2017;17:2687–95.CrossRefGoogle Scholar
  11. Saso S, Clarke A, Bracewell-Milnes T, Al-Memar M, Hamed A, Thum M, et al. Survey of perceptions of health care professionals in the United Kingdom toward uterine transplant. Prog Transplant. 2015;25:56–63.CrossRefGoogle Scholar
  12. Testa G, Anthony T, McKenna G, Koon E, Wallis K, Klintmalm G, et al. Deceased donor uterus retrieval: a novel technique and workflow. Am J Transplant. 2018;18(3):679–83.CrossRefGoogle Scholar
  13. Wranning C, Molne J, El-Akouri R, Kurlberg G, Brannstrom M. Short-term ischaemic storage of human uterine myometrium—basic studies towards uterine transplantation. Hum Reprod. 2005;20:2736–44.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Anne C. Davis
    • 1
  • Rebecca Flyckt
    • 2
  • Tommaso Falcone
    • 2
    Email author
  1. 1.IVI AmericaBasking RidgeUSA
  2. 2.Cleveland Clinic, Women’s Health InstituteClevelandUSA

Personalised recommendations