In this work, we propose a novel imaging preprocessing step based on the use of the gradient magnitude for medical DaTSCAN SPECT images. As Parkinson’s Disease (PD) is characterized by a marked reduction of intensity at striatum area, measuring intensities in this region is considered as a good marker for this neurological disorder. To extend this idea, we have been studying how quick these values decrease. A simple way to do this was using the gradient of each image. Applying Machine Learning algorithms, we have classified the gradient images and obtained an accuracy improvement of almost 2%. These results prove that the gradient magnitude is even a better marker for PD diagnosis and opens the door to new future investigations about this pathology.
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This work was supported by the MINECO/FEDER under the TEC2015-64718-R project and the Ministry of Economy, Innovation, Science and Employment of the Junta de Andalucía under the Excellence Project P11-TIC-7103.
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