Accommodating Research in Busy Bariatric Practice

  • Aaron Lee WiegmannEmail author
  • Alfonso Torquati


Weight loss surgery is an actively advancing field, in part, because of the excellent work that surgeon-scientists are undertaking while maintaining their busy practices. This chapter provides a framework for accommodating research within a busy bariatric practice. Success requires building a winning team. Creating a comprehensive bariatric program is almost a necessity and will only allow research productivity to expand. Researchers must have a nuanced understanding of the academic research process including important steps, i.e. the institutional review board. Certainly, the researcher must understand what exactly bariatric surgery research entails, including available useful testing that may allow for certain discoveries. Funding can absolutely make or break an investigator’s project, and a researcher must be fluent in application strategies to obtain coveted funding. Knowledge of these elements will provide researchers with basic skills to successfully accommodate research in a busy bariatric practice.


Bariatric surgery Research funding IRB Bariatric grant Bariatric research 


  1. 1.
    Ogden CL, et al. Prevalence of childhood and adult obesity in the United States, 2011–2012. JAMA. 2014;311(8):806–14.CrossRefPubMedPubMedCentralGoogle Scholar
  2. 2.
    The state of obesity, better policies for a healthier America. Trust for America’s Health and the Robert Wood Johnson Foundation. 2016. Accessed 20 Aug 2016.
  3. 3.
    Boyle JP, et al. Projection of the year 2050 burden of diabetes in the US adult population: dynamic modeling of incidence, mortality, and pre-diabetes prevalence. Popul Health Metrics. 2010;8(1):1.CrossRefGoogle Scholar
  4. 4.
    National Coverage Determination (NCD) for bariatric surgery for treatment of co-morbid conditions related to morbid obesity (100.1). Centers for Medicare & Medicaid Services. 2017. Accessed 20 Aug 2016.
  5. 5.
    Guidance for institutional review boards and clinical investigators, U.S. Food & Drug Administration. 01/25/2016. Accessed 15 Aug 2016.
  6. 6.
    Schauer PR, et al. Bariatric surgery versus intensive medical therapy in obese patients with diabetes. N Engl J Med. 2012;366(17):1567–76.CrossRefPubMedPubMedCentralGoogle Scholar
  7. 7. Accessed 18 Aug 2016.
  8. 8.
    Santo MA, et al. Weight regain after gastric bypass: influence of gut hormones. Obes Surg. 2016;26(5):919–25.CrossRefPubMedGoogle Scholar
  9. 9.
    Shah M, Law JH, Micheletto F, Sathananthan M, Man CD, Cobelli C, Rizza RA, Camilleri M, Zinsmeister AR, Vella A. The contribution of endogenous glucagon-like peptide-1 to glucose metabolism after Roux-en-Y gastric bypass. Diabetes. 2013: DB_130954.Google Scholar
  10. 10.
    Evans S, et al. Gastric bypass surgery restores meal stimulation of the anorexigenic gut hormones glucagon-like peptide-1 and peptide YY independently of caloric restriction. Surg Endosc. 2012;26(4):1086–94.CrossRefPubMedGoogle Scholar
  11. 11.
    Bruce JM, et al. Changes in brain activation to food pictures after adjustable gastric banding. Surg Obes Relat Dis. 2012;8(5):602–8.CrossRefPubMedGoogle Scholar
  12. 12.
    Strader AD, Woods SC. Gastrointestinal hormones and food intake. Gastroenterology. 2005;128(1):175–91.CrossRefPubMedGoogle Scholar
  13. 13.
    Patriti A, et al. The entero-insular axis and the recovery from type 2 diabetes after bariatric surgery. Obes Surg. 2004;14(6):840–8.CrossRefPubMedGoogle Scholar
  14. 14.
    Simonyte K, et al. Weight loss after gastric bypass surgery in women is followed by a metabolically favorable decrease in 11β-hydroxysteroid dehydrogenase 1 expression in subcutaneous adipose tissue. J Clin Endocrinol Metab. 2010;95(7):3527–31.CrossRefPubMedGoogle Scholar
  15. 15.
    Laferrere B, et al. Rise of oxyntomodulin in response to oral glucose after gastric bypass surgery in patients with type 2 diabetes. J Clin Endocrinol Metab. 2010;95(8):4072–6.CrossRefPubMedPubMedCentralGoogle Scholar
  16. 16.
    Chandarana K, et al. Diet and gastrointestinal bypass–induced weight loss. Diabetes. 2011;60(3):810–8.CrossRefPubMedPubMedCentralGoogle Scholar
  17. 17.
    Baena-Fustegueras JA, et al. Soluble CD40 ligand in morbidly obese patients: effect of body mass index on recovery to normal levels after gastric bypass surgery. JAMA Surg. 2013;148(2):151–6.CrossRefPubMedGoogle Scholar
  18. 18.
    Mayor S. Bariatric surgery should be an option for treating type 2 diabetes, societies say. BMJ. 2016;353:i2955.CrossRefPubMedGoogle Scholar
  19. 19.
    Wang YC, et al. Severe obesity in adults cost state Medicaid programs nearly $8 billion in 2013. Health Aff. 2015;34(11):1923–31.CrossRefGoogle Scholar
  20. 20.
    Lewis KH, et al. Comparing medical costs and use after laparoscopic adjustable gastric banding and Roux-en-Y gastric bypass. JAMA Surg. 2015;150(8):787–94.CrossRefPubMedPubMedCentralGoogle Scholar
  21. 21.
    SAGES meetings/symposia/courses/workshops. Society of American Gastrointestinal and Endoscopic Surgeons. Accessed 22 Aug 2016.
  22. 22.
    Research grant awards highlights. American Society for Metabolic and Bariatric Surgery. 2014. Accessed 22 Aug 2016.
  23. 23.
    Archive: highlights of past obesity research solicitations. NIH Obesity Research. 02/07/2017. Accessed 22 Aug 2016.
  24. 24.
    FUNDING – project listing by category. NIH Research Portfolio Online Reporting Tools (RePORT). Accessed 22 Aug 2016.
  25. 25.
    FUNDING – estimates of funding for various research, condition, and disease categories (RCDC). NIH Research Portfolio Online Reporting Tools (RePORT). 07/03/2017. Accessed 23 Aug 2016.

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of SurgeryRush University Medical CenterChicagoUSA

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