Targeted Ablative Therapies for Prostate Cancer

  • Jared S. Winoker
  • Harry Anastos
  • Ardeshir R. RastinehadEmail author
Part of the Cancer Treatment and Research book series (CTAR, volume 175)


Men diagnosed with low- to intermediate-risk, clinically localized prostate cancer (PCa) often face a daunting and difficult decision with respect to treatment: active surveillance (AS) or radical therapy. This decision is further confounded by the fact that many of these men diagnosed, by an elevated PSA, will have indolent disease and never require intervention. Radical treatments, including radical prostatectomy and whole-gland radiation, offer greater certainty for cancer control, but at the risk of significant urinary and/or sexual morbidity. Conversely, AS preserves genitourinary function and quality of life in exchange for burdensome surveillance and the psychological impact of living with cancer.


Focal therapy Prostate cancer treatment Biochemical recurrence High-intensity focused ultrasound Radiofrequency ablation Photodynamic therapy Electroporation 


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Jared S. Winoker
    • 1
  • Harry Anastos
    • 1
  • Ardeshir R. Rastinehad
    • 1
    • 2
    Email author
  1. 1.Department of UrologyIcahn School of Medicine at Mount SinaiNew YorkUSA
  2. 2.Department of RadiologyIcahn School of Medicine at Mount SinaiNew YorkUSA

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