Prophylactic Versus Selective Central Neck Dissection in Pediatric Papillary Thyroid Cancer

  • Benjamin JamesEmail author
  • Raymon H. Grogan
  • Edwin L. Kaplan
  • Peter Angelos
Part of the Difficult Decisions in Surgery: An Evidence-Based Approach book series (DDSURGERY)


The first case of thyroid carcinoma in a child was described in 1902. Following this, Crile published the first case series of pediatric thyroid cancer in 1959, whereby he characterized pediatric thyroid cancer in 18 children. He noted that pediatric thyroid cancer was more commonly metastatic to cervical lymph nodes and to the lungs than was described in the adult population. Despite finding these cancers to be more aggressive than in adults, only one of the patients died of thyroid cancer and four of them were alive with lung metastases. This publication spawned many subsequent studies confirming these findings. As a result, there has been much debate on the appropriate surgical treatment of thyroid cancer in the pediatric population both with respect to the extent of surgery and the use of radioactive iodine.


Pediatric thyroid cancer Adolescent thyroid cancer Prophylactic neck dissection Papillary thyroid cancer 


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Benjamin James
    • 1
    Email author
  • Raymon H. Grogan
    • 2
  • Edwin L. Kaplan
    • 3
  • Peter Angelos
    • 4
  1. 1.Section of Endocrine Surgery, Division of Surgical Oncology, Department of SurgeryBeth Israel Deaconess Medical CenterBostonUSA
  2. 2.Baylor College of Medicine, Michael E. DeBakey Department of Surgery, Endocrine SurgeryBaylor St. Luke’s Medical CenterHoustonUSA
  3. 3.Department of SurgeryThe University of ChicagoChicagoUSA
  4. 4.Department of Surgery and MacLean Center for Clinical Medical EthicsThe University of ChicagoChicagoUSA

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