Capripoxviruses are double-stranded DNA viruses that have hairpin loop ends which are similar to other poxviruses. Unfortunately, these regions have not yet been sequenced to directly compare these regions to the hairpin loop ends of other poxviruses. The genomes of members of the Capripoxvirus genus are approximately 150 Kbp in length. Capripoxviruses are similar to other poxviruses, with the genome being complex and encoding many genes. Before full-genome sequencing was available, restriction fragment analysis was used to compare and classify the relationship between capripoxviruses (Black et al. 1986; Gershon and Black 1988) and to some orthopoxvirus members (Gershon et al. 1989). These studies demonstrated the relationship between capripoxviruses and other poxviruses. The full-genome sequencing of lumpy skin disease virus together with bioinformatics revealed that lumpy skin disease virus encodes 156 putative genes (Tulman et al. 2001).
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