The law of Laplace relates transmural pressure with wall stress. In a (cylindrical) blood vessel and in a (spherical) heart model there exists a simple relation between pressure and circumferential wall stress. The law gives the average stress over the wall, thus how the stress varies over the wall cannot be derived. The law holds only for simple geometries, such as cylindrical blood vessels. Cardiac wall stress estimates require more sophisticated models.
KeywordsTransmural pressure Wall thickness Wall stress Cylinder Sphere Geometry
- 7.Love AEH. A treatise on mathematical elasticity. 3rd ed. London & New York: Cambridge University Press; 1952.Google Scholar