Solid-Phase Extraction with Packed-Fiber is a Biological Sample Preparation Tool for Neuro-Active Molecule Detection

  • Lei Ma
  • Xiaoyan Shen
  • Xuejun Kang
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1072)


Neurotransmitters play a major role in shaping everyday life and functions. Accurate analytical methods are needed for detection of neurotransmitters. Packed-fiber solid-phase extraction (PFSPE) has been developed and seems to be an efficient method. This novel method is based on use of an electrospun polymer device, based on nanofibers. This strategy will be helpful for the development of real-time methods and techniques with high sensitivity to detect target neurotransmitters with high efficiency. Here we provide a brief overview of PFSPE and its applications for the determination of neuro-active molecules.



This project was Supported by Major Program of National Natural Science Foundation of China (61534003), Natural Science Foundation of Jiangsu Province of China (BK20170448), Social Science Foundation of National Department of Education (17YJC890022) , Social Science Foundation of Jiangsu Province(17TYC003), and Natural Science Foundation of Jiangsu Province Higher education of China (16KJB180019).


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© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Lei Ma
    • 1
  • Xiaoyan Shen
    • 1
  • Xuejun Kang
    • 2
  1. 1.School of Electronic InformationNantong UniversityNantongChina
  2. 2.Key Laboratory of Child Development and Learning Science, Ministry of Education, Southeast University, Research Center for Learning ScienceNanjingChina

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