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Crystallization

  • Anthony J. Hickey
  • Stefano Giovagnoli
Chapter
Part of the AAPS Introductions in the Pharmaceutical Sciences book series (AAPSINSTR)

Abstract

Crystallization is the physical process of forming a crystalline material from a liquid, gas, or amorphous solid. The control of the crystallization process has several implications in the pharmaceutical field and a strong valence in the determination of API and excipient properties, which impact solid dosage form performance. Lack of control on the dynamics of crystal equilibria is detrimental to manufacturing and stability of pharmaceutical dosage forms. Such an increased awareness has fostered the development of advanced powder technologies.

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Copyright information

© American Association of Pharmaceutical Scientists 2018

Authors and Affiliations

  • Anthony J. Hickey
    • 1
  • Stefano Giovagnoli
    • 2
  1. 1.Discovery Science and TechnologyRTI InternationalResearch Triangle ParkUSA
  2. 2.Department of Pharmaceutical SciencesUniversity of PerugiaPerugiaItaly

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