Advertisement

A New Device for Crossing Chronic Total Occlusions

  • L.-P. Riel
  • S. Dion
  • M. Charlebois-Ménard
  • M. BrouilletteEmail author
  • S. Bérubé
  • M.-A. Despatis
  • A. Benko
  • M.-É. Clavet
  • M.-J. Bertrand
  • P. Geoffroy
  • J.-F. Tanguay
Conference paper

Abstract

We report on the design and testing of a new minimally invasive device for crossing chronic total occlusions in the coronary and peripheral vasculature. The device is based on a novel shock wave generator that exploits inverse dispersion in solid waveguides to amplify the signal of broadband piezoelectric ultrasound transducers. Results of tests assessing the safety, efficacy, and mechanism of action of the device on a variety of surrogates, ex vivo arteries, and live animals are presented.

References

  1. 1.
    A.R. Galassi et al., Appropriateness of percutaneous revascularization of coronary chronic total occlusions: An overview. Eur. Heart J. 37, 2692 (2016)CrossRefGoogle Scholar
  2. 2.
    H. Al-Ameri et al., Devices to treat peripheral chronic total occlusions. J. Interv. Cardiol. 25, 395 (2012)CrossRefGoogle Scholar
  3. 3.
    G. Sianos et al., Recanalisation of chronic total coronary occlusions: 2012 consensus document from the EuroCTO club. EuroIntervention 8, 139 (2012)CrossRefGoogle Scholar
  4. 4.
    H.C. Wijeysundera et al., Relationship between initial treatment strategy and quality of life in patients with coronary chronic total occlusions. EuroIntervention 9, 1165 (2014)CrossRefGoogle Scholar
  5. 5.
    A.R. Galassi et al., Retrograde recanalization of chronic total occlusions in Europe: Procedural, in-hospital, and long-term outcomes from the multicenter ERCTO registry. J. Am. Coll. Cardiol. 65, 2388 (2015)CrossRefGoogle Scholar
  6. 6.
    M. Brouillette, S. Dion, L.-P. Riel, Mechanical Wave Generator and Method Thereof, U.S. Patent Application No. 61/377,519 (2010), International Patent Application No. PCT/US2011/049573 (2011)Google Scholar
  7. 7.
    M. Brouillette, S. Dion, L.-P. Riel, Method and System for Generating Mechanical Pulses, U.S. Patent Application No. 62/161,647 (2015), International Patent Application No. PCT/IB2016/052339 (2016)Google Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2019

Authors and Affiliations

  • L.-P. Riel
    • 1
    • 2
  • S. Dion
    • 1
    • 2
  • M. Charlebois-Ménard
    • 1
    • 2
  • M. Brouillette
    • 1
    • 2
    Email author
  • S. Bérubé
    • 3
  • M.-A. Despatis
    • 3
  • A. Benko
    • 3
  • M.-É. Clavet
    • 4
  • M.-J. Bertrand
    • 4
  • P. Geoffroy
    • 4
  • J.-F. Tanguay
    • 4
  1. 1.Shock Wave LaboratoryUniversité de SherbrookeSherbrookeCanada
  2. 2.SoundBite Medical SolutionsMontréalCanada
  3. 3.Sherbrooke University Hospital (CHUS)SherbrookeCanada
  4. 4.Montreal Heart InstituteMontréalCanada

Personalised recommendations