Intracellular Ca2+ Increase Evoked by Single Acoustic Pulses
Shock wave therapies require cellular responses. However, how shock waves interact with cells remains elusive. In this study, it was asked whether pressure discontinuities at wave fronts of shock waves are indispensable for evoking cellular responses. With shock wave irradiations, intracellular Ca2+ increase was evoked in endothelial cells. This cellular response was independent of pressure increment at front of shock waves. These results suggest that pressure discontinuity at wave front is not indispensable for evoking the cellular response.
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