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Emergency!

  • Mark T. Friedman
  • Kamille A. West
  • Peyman Bizargity
  • Kyle Annen
  • Jeffrey S. Jhang
Chapter

Abstract

A 22-year-old man is brought to the emergency department after sustaining a motor vehicle accident and hemorrhagic shock. The massive transfusion protocol (MTP) is activated, and the patient receives two trauma packs (each pack containing five units of uncrossmatched group O-negative red blood cells [RBCs], five units of type AB plasma, and one unit of apheresis platelets [any ABO type]). Subsequently, a type and screen sample (ethylenediaminetetraacetic acid [EDTA] anticoagulant) is submitted to the blood bank.

Keywords

AB plasma Dilutional thrombocytopenia Massive transfusion 

References

  1. 1.
    Borgman MA, Spinella PC, Perkins JG, Grathwohl KW, Repine T, Beekley AC, et al. The ratio of blood products transfused affects mortality in patients receiving massive transfusions at a combat support hospital. J Trauma. 2007;63(4):805–13.CrossRefGoogle Scholar
  2. 2.
    Holcomb JB, Tilley BC, Baraniuk S, et al.; PROPPR Study Group. Transfusion of plasma, platelets, and red blood cells in a 1:1:1 vs a 1:1:2 ratio and mortality in patients with severe trauma. The PROPPR randomized clinical trial. JAMA. 2015;313(5):471–82.Google Scholar
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    Zielinski MD, Johnson PM, Jenkins D, Goussous N, Stubbs JR. Emergency use of prethawed Group A plasma in trauma patients. J Trauma Acute Care Surg. 2013;74(1):69–74.CrossRefGoogle Scholar
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    Dunbar NM, Yazer MH. Safety of the use of group A plasma in trauma: the STAT study. Transfusion. 2017;57(8):1879–84.CrossRefGoogle Scholar

Recommended Reading

  1. Borgman MA, Spinella PC, Perkins JG, et al. The ratio of blood products transfused affects mortality in patients receiving massive transfusions at a combat support hospital. J Trauma. 2007;63(4):805–13.CrossRefGoogle Scholar
  2. Lal DS, Shaz BH. Massive transfusion: blood component ratios. Curr Opin Hematol. 2013;20(6):521–5.CrossRefGoogle Scholar
  3. Young PP, Cotton BA, Goodnough LT. Massive transfusion protocols for patients with substantial hemorrhage. Transfus Med Rev. 2011;25(4):293–303.CrossRefGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Mark T. Friedman
    • 1
  • Kamille A. West
    • 2
  • Peyman Bizargity
    • 3
  • Kyle Annen
    • 4
  • Jeffrey S. Jhang
    • 1
  1. 1.Icahn School of MedicineMount Sinai Health SystemNew YorkUSA
  2. 2.Department of Transfusion MedicineNational Institutes of Health Clinical CenterBethesdaUSA
  3. 3.Department of Molecular & Human GeneticsBaylor College of MedicineHoustonUSA
  4. 4.Department of PathologyChildren’s Hospital ColoradoAuroraUSA

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