A 24-year-old woman, gravida 1, para 0 (G1P0), at 38 weeks of gestation presents to labor and delivery for spontaneous rupture of membranes. Her pregnancy was uneventful. A baby girl is delivered 13 h later by normal spontaneous vaginal delivery. The baby’s Apgar scores are 8 and 9 at 1 and 5 min, respectively. Shortly after being taken to the nursery, the nurse notices that the baby has diffuse petechiae on the face, scalp, and shoulders. The mother’s hemoglobin is 12.8 g/dL, and the platelet count is 182 K/μL. Meanwhile, the neonatal hemoglobin is 19.8 g/dL, and the platelet count is 32 K/μL. Samples for both the mother and the baby (cord blood sample) (ethylenediaminetetraacetic acid [EDTA] anticoagulant) are submitted to the blood bank.
KeywordsAnti-HPA-1a Fetal and neonatal thrombocytopenia/FNAIT Modified antigen-capture enzyme-linked immunosorbent assay/MACE Monoclonal antibody immobilization of platelet antigens/MAIPA Washed platelets
- 1.Epinoza JP, Caradeux J, Norwitz ER, Illanes SE. Fetal and neonatal alloimmune thrombocytopenia. Rev Obstet Gynecol. 2013;6(1):e15–21.Google Scholar