All Washed Up
A 22-year-old man with a history of homozygous factor (F)V deficiency (Owren’s disease) is admitted for an elective right knee arthroscopy. Coagulation laboratory studies show prothrombin time (PT) 18.6 s and activated partial thromboplastin time (aPTT) 55.1 s. A type and screen (ethylenediaminetetraacetic acid [EDTA] anticoagulant) sample is submitted to the blood bank along with a request for three units of fresh frozen plasma (FFP) for preoperative transfusion.
KeywordsAnaphylactic transfusion reaction Factor V deficiency Haptoglobin deficiency IgA deficiency Platelet additive solution Solvent/detergent plasma Washed red blood cells
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