Mix and Match
A 50-year-old woman with acute myeloid leukemia (AML) receives a hematopoietic stem cell transplant (HSCT) from a human leukocyte antigen (HLA)-matched (10/10 antigens) related donor (peripheral blood stem cells [PBSC] collected via apheresis with stimulation by granulocyte colony-stimulating factor [G-CSF] and containing at least 5 × 106 CD34+ cells/kg) post-induction chemotherapy and myeloablative conditioning. The patient and donor ABO/Rh types and antibody screens are shown below (ethylenediaminetetraacetic acid [EDTA] anticoagulant samples).
KeywordsGraft-versus-host disease/GVHD HLA matching Hematopoietic stem cell transplant Major incompatibility Marrow stem cells Minor incompatibility Passenger lymphocyte syndrome Peripheral blood stem cells Pure red cell aplasia Umbilical cord blood stem cells
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